Animal Mitochondria: Evolution, Function, and Disease

Tao, Min; You, Cuiping; Zhao, Rurong; Liu, S.-J.; Zhang, Z.-H.; Zhang, C.; Liu, Y.

doi:10.2174/15665240113136660081

Cited by 32 publications

(20 citation statements)

References 96 publications

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“…Mt genomes have been extensively used as genetic markers in molecular phylogenetic studies due to it having several useful properties (i.e., haploidy, compactness, maternal inheritance, relatively high mutation rates, and the lack of recombination) [3]. To date, there are over 4000 complete mt genome sequences of metazoans available in GenBank, including some from parasites [4-10].…”

Section: Introductionmentioning

confidence: 99%

The complete mitochondrial genome of the scab mite Psoroptes cuniculi (Arthropoda: Arachnida) provides insights into Acari phylogeny

Song

et al. 2014

Parasites Vectors

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BackgroundLimited available sequence information has greatly impeded population genetics, phylogenetics and systematics studies in the subclass Acari (mites and ticks). Mitochondrial (mt) DNA is well known to provide genetic markers for investigations in these areas, but complete mt genomic data have been lacking for many Acari species. Herein, we present the complete mt genome of the scab mite Psoroptes cuniculi.MethodsP. cuniculi was collected from a naturally infected New Zealand white rabbit from China and identified by morphological criteria. The complete mt genome of P. cuniculi was amplified by PCR and then sequenced. The relationships of this scab mite with selected members of the Acari were assessed by phylogenetic analysis of concatenated amino acid sequence datasets by Bayesian inference (BI), maximum likelihood (ML) and maximum parsimony (MP).ResultsThis mt genome (14,247 bp) is circular and consists of 37 genes, including 13 genes for proteins, 22 genes for tRNA, 2 genes for rRNA. The gene arrangement in mt genome of P. cuniculi is the same as those of Dermatophagoides farinae (Pyroglyphidae) and Aleuroglyphus ovatus (Acaridae), but distinct from those of Steganacarus magnus (Steganacaridae) and Panonychus citri (Tetranychidae). Phylogenetic analyses using concatenated amino acid sequences of 12 protein-coding genes, with three different computational algorithms (BI, ML and MP), showed the division of subclass Acari into two superorders, supported the monophylies of the both superorders Parasitiformes and Acariformes; and the three orders Ixodida and Mesostigmata and Astigmata, but rejected the monophyly of the order Prostigmata.ConclusionsThe mt genome of P. cuniculi represents the first mt genome of any member of the family Psoroptidae. Analysis of mt genome sequences in the present study has provided new insights into the phylogenetic relationships among several major lineages of Acari species.

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Section: Introductionmentioning

confidence: 99%

The complete mitochondrial genome of the scab mite Psoroptes cuniculi (Arthropoda: Arachnida) provides insights into Acari phylogeny

Song

et al. 2014

Parasites Vectors

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“…Some properties of mitogenome, i.e. maternal inheritance, relatively high mutation rates, and the lack of recombination contribute to the broad consensus that mitogenome is widely regarded as genetic markers in molecular phylogenetic studies (Dermauw et al 2009;Gu et al 2014;Tao et al 2014).…”

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confidence: 99%

The complete mitochondrial genome and phylogenetic analysis of Haemaphysalis longicornis Neumann (Acari: Ixodidae)

Geng

Zheng

Zou

et al. 2017

Mitochondrial DNA Part B

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Haemaphysalis longicornis ticks are vectors or reservoirs of numerous infectious pathogens and cause a variety of human and animal diseases worldwide. However, there is limited knowledge on available genetic sequence. Herein, we extracted the complete mitochondrial genome (mitogenome) from enriched mitochondria of H. longicornis first time in ticks and gained its sequence with 14,718bp in length. The mitogenome consisted of 13 PCGs, 22 tRNA, 2 rRNA, and 2 noncoding regions. Also, the monophyletic phylogenetic position of H. longicornis is inferred based on 28 complete mitogenomes in total comprised of various species from Ixodida ticks in addition to the mitogenome of H. longicornis.

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“…Los datos obtenidos muestran que a concentraciones mayores a 50μg/ml este metabolito puede afectar los complejos I, III y la ATPasa; y se ha establecido que deficiencias en el funcionamiento de estos complejos enzimáticos está asociados con varios síndromes clínicos como acidosis láctica, cardiomiopatía y cataratas (51)(52)(53). Igualmente, el aumento en las especies reactivas de oxígeno en la mitocondria, producto de deficiencias en el complejo I y III se han relacionado con el desarrollo y empeoramiento de enfermedades neurodegenerativas como Parkinson, enfermedad de Alzheimer, esclerosis lateral amiotrópica y enfermedad de Huntington (39,(54)(55)(56).…”

Section: Discussionunclassified

Linalool effect on mitochondrial bioenergetics rat liver

Bueno-Duarte

Méndez‐Sánchez

2015

Vitae

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RESUMENAntecedentes: El linalool (2,6-dimetil-2,7-octadien-6-ol) es un monoterpeno presente en más de 200 tipos de plantas, y constituye el componente mayoritario de varios aceites esenciales. El linalool posee una amplia variedad de potenciales propiedades farmacológicas; que van desde propiedades antisépticas, ansiolíticas, anti-inflamatorias, antifúngicas, antimicrobianas y proapotóticas en diferentes líneas de cé-lulas tumorales. Sin embargo, su principal uso está relacionado como una molécula odorante o fragancia en productos de uso tópico en productos cosméticos y en la industria del perfume. Objetivo: En este estudio se evaluó el efecto del linalool sobre la bioenergética de mitocondrias aisladas de hígado de rata. Métodos: El linalool en concentraciones entre (5-100μg/mL) fue evaluado en mitocondrias aisladas de ratas machos albinas raza Wistar, de acuerdo al método descrito por Voss et al (1961). Inicialmente, se determinó el consumo de oxígeno en mitocondrias intactas mediante un método polarográfico por medio de un oxígrafo. Posteriormente, se determinó el efecto del compuesto sobre las enzimas de la cadena respiratoria mitocondrial usando métodos polarográficos y espectrofotométricos. Resultados: Los resultados obtenidos indican que el linalool en las concentraciones de 5, 10, 50 y 100μg/mL, afecta la velocidad de consumo de oxígeno en el estado 3 y 4 de mitocondrias energizadas con glutamato-malato y succinato. Sin embargo, el efecto inhibitorio es mayor al usar glutamato-malato como sustrato. Por su parte, el análisis de la actividad de las enzimas de la cadena respiratoria mitocondrial mostró que el linalool (50μg/mL) inhibe los complejos I, III y la actividad ATPasa. Conclusiones: El linalool inhibe el complejo I, complejo III y la ATPasa, esta inhibición podría aumentar la generación de especies reactivas de oxígeno.Palabras clave: Linalool, mitocondria, enzimas, consumo de oxígeno. ABSTRACTBacground: The linalool (2,6-dimethyl-2 ,7-octadiene-6-ol) is a monoterpene present in more than 200 types of plants, and it is the major component of several essential oils. The linalool has a wide range of potential pharmacological properties, such as antiseptic, anxiolytic, anti-inflammatory, antifungal, antimicrobial and proapoptotic in different tumor cell lines. However, its primary use is associated as

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Animal Mitochondria: Evolution, Function, and Disease

Cited by 32 publications

References 96 publications

The complete mitochondrial genome of the scab mite Psoroptes cuniculi (Arthropoda: Arachnida) provides insights into Acari phylogeny

The complete mitochondrial genome of the scab mite Psoroptes cuniculi (Arthropoda: Arachnida) provides insights into Acari phylogeny

The complete mitochondrial genome and phylogenetic analysis of Haemaphysalis longicornis Neumann (Acari: Ixodidae)

Linalool effect on mitochondrial bioenergetics rat liver

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