Animal Experiments Used in Experimental Neuroscience Research: Learning, Memory, Anxiety, Depression and Motor Function Behavioural Experiments

Abstract

Behavioral experiments have been conducted since the classical conditioning research of Ivan Pavlov in 1904. Experimental research plays an important role in understanding the mechanisms of diseases, preventing these diseases, and developing effective treatment methods. Research using animal models is very important to understand the mechanisms of these diseases and to develop effective treatment strategies. Animal models are widely used in the research of a treatment method, the development of novel treatment protocols, and the discovery of new drug molecules. The efficacy of the drug to be developed is very important both for testing whether the animal model is formed before starting the research and for the effectiveness of the drug in treatment and for the elucidation of the mechanisms to be investigated. Therefore, evaluations are usually made with behavioral experiments. Each behavioral experiment has its own advantages and disadvantages. Therefore, the researcher should be aware of these advantages and limitations before choosing the most appropriate behavioral experiment. This review aimed to describe the most commonly used learning, memory, anxiety, depression, and motor function behavioral experimental protocols in experimental models such as Alzheimer's, epilepsy, migraine, neuropathic pain, schizophrenia, Parkinson's, cerebral ischemia, and traumatic brain injury.