Angiotensin I-converting enzyme (ACE) inhibitory peptides derived from arachin by simulated gastric digestion

Screening, discovery, and characterization of angiotensin-I converting enzyme inhibitory peptides derived from proteolytic hydrolysate of bitter melon seed proteins

“…4. VY-7 and VG-8 showed IC 50 values comparable to those of other ACEI peptides derived from other protein sources [42][43][44]. However, the IC 50 value of VY-7 is superior to those of most of the other ACEI peptides containing a similar number of amino acid residues reported in the literature [45][46][47][48].…”

ACE inhibitory activity of pangasius catfish (Pangasius sutchi) skin and bone gelatin hydrolysate

“…Proline is one of the crucial amino acid residues involved in ACE inhibitory activity (Meisel 2005). The occurrence of amino acid Pro at the C-terminal sequence of several strong ACE inhibitory peptides, isolated from different protein hydrolysates have been reported (Fujita et al 2000;Jimsheena and Gowda 2011;Majumder and Wu 2011;Wijesekara et al 2011). The amino acid compositions of P. sutchi skin and bone gelatins and their corresponding hydrolysate fractions are summarized in Table 2.…”

Database of Biologically Active Proteins and Peptides

“…This option was used by Bauchart et al (2007) and Català-Clariana et al (2010). The prediction of the ACE inhibitory activity of proteins followed by the experimental measurements of the activity was described as exemplified by the proteins from amaranthus (Vecchi and Añón 2009;Fritz et al 2010) or peanut (Jimsheena and Gowda 2011). Examples of the application of the BIOPEP database encourage us to conclude that it has become a valuable tool for food scientists.…”