Angiotensin‐converting enzymes 1 and 2 in the feces: presence and catalytic activity in the rat 2,4,6‐trinitrobenzene sulfonic acid‐induced model of colitis
Mariana Ferreira‐Duarte,
Lilian Caroline Gonçalves Oliveira,
Clara Quintas
et al.
Abstract:Background and AimInflammatory bowel disease is challenging to diagnose. Fecal biomarkers offer noninvasive solutions. The renin–angiotensin‐aldosterone system is implicated in intestinal inflammation. Angiotensin‐converting enzyme (ACE) and angiotensin‐converting enzyme 2 (ACE2) regulate its activity, but conflicting findings on these enzymes in colitis require further investigation. We aimed to assess ACE and ACE2 presence and activities in the feces, serum, and colon of 2,4,6‐trinitrobenzene sulfonic acid (… Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.