Angiosarcoma Which Developed on the Abdominal Wall: Report of a Case

Abstract

We report a 68-year-old Japanese woman with angiosarcoma (AS) on the abdominal wall. To the best of our knowledge, she is the third such patient reported from Japan.

Spindle cell angiosarcoma following irradiation therapy for cervical carcinoma

“…We catheterized from the left subclavicular artery and placed the catheter tip just under the superior mesenteric artery. rIL 2 therapy is rarely performed for angiosarcomas in areas other than the scalp and face 17, (c)23 . Furthermore, although intra‐arterial one‐shot injection of rIL 2 through the external carotid artery 24 or superficial temporal artery 25 has been reported, that through the abdominal aorta via the left subclavicular artery has not been reported to our knowledge.…”

“…A past review of 20 cases of postradiation angiosarcomas demonstrated adjacent evidence of radiation dermatitis in five cases, but none in one 11 . Another report also described similar cases without radiation dermatitis 17 . Since most descriptions did not describe the presence or absence of radiation dermatitis, the frequency was unknown.…”

Case report of an angiosarcoma of the abdominal wall during liraglutide injections: A coincidence?

“…Other documented sarcomas of the abdominal wall include undifferentiated pleomorphic sarcomas, fibrosarcomas, and synovial sarcomas [4] . The lower abdominal wall is an exceptional location for angiosarcoma [7] , [14] , and was only rarely described in case reports and small series [2] . In the largest prospective study, the Memorial Sloan-Kettering Cancer Center group identified 85 cases of soft tissue tumors of the abdominal wall from 1982 and 1999.…”

“…Angiosarcoma is a very rare but highly aggressive malignant vascular tumor [2] , [3] , [4] , [5] accounting for 1 % to 4 % of all soft tissue sarcomas [2] , [3] , [4] , [5] , [6] . Localized angiosarcoma of the abdominal wall is so infrequent that only few anecdotal cases were reported in the literature [3] , [7] , [8] , [9] , [10] , [11] , [12] , [13] , [14] . Identified risk factors include chronic lymphedema, radiation therapy, chronic sun or chemical toxin exposure, foreign bodies, immunosuppression, and familial syndromes including neurofibromatosis (NF-1), BRCA-1 and BRCA-2 mutations and Klippel-Trenaunay syndromes [2] , [5] .…”