Angiosarcoma of the Breast

Lim, R.F.; Goei, R.

doi:10.1148/rg.27si075016

Cited by 34 publications

(29 citation statements)

References 20 publications

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“…CD31 seems to be the most sensitive and specific for endothelial differentiation. Endothelial marker study by immunostaining is must to arrive at final diagnosis [5,6] .The markers are positive usually in grade I and II. However, negative in poorly differentiated histological features.…”

Section: Discussionmentioning

confidence: 99%

An interesting pathological diagnosis: Angiosarcoma of breast

Ingle¹,

Girji²

2016

Adv Mod Oncol Res

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Primary angiosarcoma of breast is an extremely unusual variant of breast malignancies and its incidence is about 0.05% of all primary breast malignancies. Herein, we are presenting an unusual case of an 84 year old female patient with primary angiosarcoma of breast, which was diagnosed by fine needle aspiration cytology (FNAC) and confirmed with histopathology and immunohistochemistry approaches. She was treated with modified radical mastectomy (MRM), followed by radiotherapy and was observed to be recovering well based on the last 10 months of her post-treatment follow-up visit.

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Section: Discussionmentioning

confidence: 99%

An interesting pathological diagnosis: Angiosarcoma of breast

Ingle¹,

Girji²

2016

Adv Mod Oncol Res

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“…When examined with ultrasound, these lesions present variable characteristics, being able to adopt a hypoechoic, hyperechoic, or heterogeneous appearance with or without posterior acoustic shadowing [14]. Radiographically, the finding of skin thickening by mammography or nuclear magnetic resonance (MRI), or the appearance of skin lesions that enhance the contrast in the MRI may raise the suspicion of this secondary tumour lesion [2].…”

Section: Discussionmentioning

confidence: 99%

Radiation-induced breast angiosarcoma: a case report

Tato-Varela

Albalat-Fernández

Pabón-Fernández

et al. 2016

ecancer

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Radiation-induced breast angiosarcoma is a severe but rare late complication in the breast-preserving management of breast cancer through surgery and radiotherapy [1]. Often the initial diagnosis of this entity is complex given its relatively anodyne nature and usually being present in the form of typically multifocal reddish-purple papular skin lesions [2]. Because of the low incidence of this tumour, there is a limited number of studies regarding its optimal therapeutic management [3]. The preferred treatment is aggressive surgical removal and the prognosis is poor with an overall survival rate of 12–20% at five years [4].

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“…When it occurs in the breast, it affects women in their 3rd and 4th decade and accounts for one in 1700-2300 cases of primary breast cancer. 8 It arises in the breast more often than in any other organ. 3 The size and location of palpable masses vary from small cutaneous nodules (the cutaneous subtype) to large lumps that constitute the entire breast (the cutaneous subtype).…”

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confidence: 99%

“…Ultrasound reveals a lesion that may appear hypoechoic, hyperechoic, or a heterogeneous region, with or without acoustic shadowing. 8 Angiosarcoma is divided into low and high histologic grades. Grade is prognostically siginificant.…”

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confidence: 99%