Angioplastia pulmonar con balón en la hipertensión pulmonar tromboembólica crónica no operable. Estudio observacional en una unidad de referencia

Mid‐term follow‐up of balloon pulmonary angioplasty for inoperable chronic thromboembolic pulmonary hypertension: An experience in Latin America

“…More than 75% of the patients were women, with a mean age of 59 ± 12.7 years, similar to what has been reported in Asian population and slightly younger than the European cohorts 9,17,18,21 . On the other hand, >80% of the patients had a history of thromboembolic events, which is similar to what is observed in other Western countries 9,19‐21 . Most patients were highly symptomatic, with 25% of them in functional class IV and 27.3% needing permanent oxygen therapy, clear indicators of a very sick population.…”

“…16 There is still a gap in knowledge regarding the mid-and long-term results of BPA, although some registries have reported hemodynamic, clinical and survival benefits similar to PEA, up to 43 months of FU. [17][18][19][20][21] Moreover, no mid-terms FU of BPA have been reported in our country, nor experiences from other centers compiled in a single data set. The objective of this study is to report the mid-term results of BPA for inoperable CTEPH, based on a Chilean multicenter prospective registry.…”

“…The results of this registry are consistent with other similar publications, which included the learning curve. A BPA registry of 46 patients, from a PAH reference center in Spain, showed significant reductions in PVR by 44% (10.1 ± 4.9 vs. 5.6 ± 2.2 WU; p < .001) and mPAP by 23.6% (49.5 ± 12 vs. 37.8 ± 9 mmHg; p < .001) 20 . They also reported an improvement in 6MWD by 74 m (394 vs. 468 m; p = .001).…”

“…VC were frequent, but not different to what has been described in other registries. 9,19,20 Only one patient (4.5%) developed LRI and was successfully treated without the need for invasive mechanical ventilation. It has been suggested that LRI is less dependent on flow, as it is the case in PEA, and more closely related to iatrogenic vascular injury.…”

“…There is still a gap in knowledge regarding the mid‐ and long‐term results of BPA, although some registries have reported hemodynamic, clinical and survival benefits similar to PEA, up to 43 months of FU 17‐21 . Moreover, no mid‐terms FU of BPA have been reported in our country, nor experiences from other centers compiled in a single data set.…”