Angiomyolipoma (Hamartoma) of the Kidney

Rupture of a renal angiomyolipoma (hamartoma)

“…It is caused by an autosomal dominant hereditary gene and is characterized by epilepsy, mental retardation and skin manifestation (adenoma sebaceum cyst). According to various authors, 50-80% of patients with tuberose sclerosis have additional renal hamartomas (McCullough et al, 1971;Becker et al, 1973;Honey and Honey, 1977). kidneys, chest, heart and skeletal bones.…”

“…They are mostly small, multiple, multifocal and involve both kidneys. In patients without tuberose sclerosis they are usually unilateral, solitary and relatively larger (Becker et al, 1973). Histologically the two forms are identical (Hajdu and Foote, 1969).…”

“…McCullough, Scott and Seybold (1971), Becker et al (1973), Honey and Honey (1977) consider that 50-80% of renal hamartomas appear in patients with tuberose sclerosis. Angiomyolipomas without tuberose sclerosis are usually solitary and unilateral.…”

Lipomatous Tumors of the Kidney and Adrenal: Apparent Echographic Specificity

“…Patients with tuberous sclerosis and diffuse hamartomas present at a younger age than those with isolated lesions, and the sex differential is less striking. An interesting feature is the predominance of right-sided lesions, apparently representing nearly 80 % of the solitary tumors (1,14). As many as 25 % of these tumors may arise in an extrarenal location, including the renal sinus (4,14).…”

“…The isolated lesion may be a difficult diagnostic problem. Much has been written about characteristic angiographic findings (1,3,13). The presence of multiple small aneurysms of the interlobar and interlobular arteries is said to be highly suggestive of angiomyolipoma.…”