Angiomyofibroblastoma-Like Tumor of the Scrotum

Lee, Seung Hyun; Yang, Jung Wook; Do, Jung Mo; Seo, Deok Ha; Jung, Jae Hun; Kihan, Chung; Lee, Jong Sil; Hyun, Jae Seog

doi:10.4111/kju.2010.51.5.365

Cited by 11 publications

(19 citation statements)

References 5 publications

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“…12 This was the case for our tumour, which contained no evidence of prostatic, rectal or urethral tissue. This is interesting given the close approximation to these structures and the urethral adherence found during surgical dissection.…”

Section: Discussionmentioning

confidence: 59%

“…10,11 Conversely, CAFs are definitively treated by simple excision and no clear recurrence has ever been noted. 6,12,13 Therefore, removal and clinical follow-up is an adequate long-term plan and our patient was still disease-free at the 9-month follow up.…”

Section: Discussionmentioning

confidence: 72%

“…6,12,13 Therefore, removal and clinical follow-up is an adequate long-term plan and our patient was still disease-free at the 9-month follow up.…”

Section: 2mentioning

confidence: 72%

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A large cellular angiofibroma of the male pelvis presenting with obstructive voiding: A case report and review of the literature

Emtage

Parker

Marcet

et al. 2013

CUAJ

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Cellular angiofibromas (CAF) are rare, benign soft-tissue tumours. The diagnosis of CAF is important given the heavy resemblance to other tumours. Herein, we describe a case of a rapidly growing, very large (13.5 cm) CAF located in the deep pelvis of a middleaged male who presented with difficulty voiding. IntroductionCellular angiofibromas (CAF) are rare, benign soft-tissue tumours first described by Nucci and colleagues in 1997. 1 CAF share pathological features of angiomyofibroblastoma and aggressive angiomyxoma (AAM), but do not fall into either category. The masses are well-circumscribed, typically less than 3.0 cm and show marked female predominance. In 1998, Laskin and colleagues reported 11 of these tumours in male genitalia, 2 and since then there have been only a few case reports. Most have been found in women, primarily in the vulva. [3][4][5] In males, most are found in the scrotum and inguinal region, averaging about 5 to 6 cm in size.2,3 The diagnosis of CAF is important given the heavy resemblance to other tumours, such as AAM, which is known to have a very high rate of local recurrence. 4 Herein, we describe the case of a rapidly growing, very large (13.5 cm) CAF located in the deep pelvis of a middle-aged male who presented with difficulty voiding. Case presentationA 58-year-old man initially presented with right groin/pelvic pain radiating down into his scrotum, as well as decreased urinary flow and decreased ejaculation. Due to refractory symptoms, a computed tomography (CT) scan of the abdomen and pelvis was done which showed a 7 × 7 × 5-cm mass to the right of the prostate extending down to the bulbar urethra. Prior attempts at both transurethral drainage and transperineal aspiration were unsuccessful and he was then referred to our clinic. A pelvic magnetic resonance imaging (MRI) revealed substantial growth; a 11-cm wellcircumscribed lesion abutting the rectum and displacing the urinary bladder and prostate proximally (Fig. 1, Fig. 2). Biopsies showed a benign stromal tumour of genitourinary origin. Resection was recommended via combined abdominal/perineal approach with colorectal surgery and urology.Exploratory laparotomy showed a large encapsulated mass occupying the entirety of the lower pelvis. The mass was dissected off of the prostate with relative ease, but was more difficult distally owing to dense adherence to a 3-cm portion on the anterior surface of the bulbar urethra. The mass was carefully freed from the rectum through the perineal incision. Ultimately, the intact mass in its entirety was removed with no evidence of residual disease. The specimen was sent to pathology and was read as a large benign spindle cell tumour mostly consistent with a CAF. Gross descriptionThis was an encapsulated, well-circumscribed mass with a thin fibrous capsule. It was elongated and measured 13.5 × 7.4 × 3.7 cm (Fig. 3). The mass felt rubbery and sectioning revealed a gelatinous, tan-pink to grey surface that was focally trabeculated. Microscopic descriptionThe mass consisted of loosely ar...

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Section: Discussionmentioning

confidence: 59%

Section: Discussionmentioning

confidence: 72%

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A large cellular angiofibroma of the male pelvis presenting with obstructive voiding: A case report and review of the literature

Emtage

Parker

Marcet

et al. 2013

CUAJ

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“…Histologically, the nomenclature, angiofibroblastoma, is based on the two main components of the tumor: blood vessels and connective tissue. This has been observed in the majority of reported cases [1–9]. The tumor is well circumscribed, even encapsulated [1, 2, 5, 7, 10].…”

Section: Discussionmentioning

confidence: 82%

Paratesticular Angiomyofibroblastoma-Like Tumor: Unusual Case of a Solidocystic Form

Msakni

Ghachem

Bani

et al. 2017

Case Reports in Medicine

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The angiomyofibroblastoma-like tumor of the male genital tract is a rare benign tumor. A total of 34 cases have been reported in the literature. We herein report an exceptional case of solidocystic form in its paratesticular location, in a 79-year-old man. Clinical examination objectified a right testicular induration. Macroscopic examination of the orchidectomy objectified a paratesticular solidocystic tumor formation. Microscopically, the solid area was composed of vessels with small caliber and turgidity of endothelial cells. These vessels were surrounded by clusters of epithelioid cells, sometimes having the appearance of giant cells. They were associated with spindle cells. The cystic area was uncoated. Immunohistochemically, the fusiform cells expressed Desmin and Smooth Muscle Actin. Endothelial cells and clusters of cells surrounding large vessels expressed CD34. The expression of receptors for estrogen and progesterone was negative. To our knowledge, this is the second solidocystic case of angiomyofibroblastoma-like tumor of male genital tract.

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“…It is observed in elderly men as a slowly growing asymptomatic lesion. Only sporadic case reports of angiomyofibroblastoma‐like tumors exist in the literature …”

Section: Paratesticular Benign Tumorsmentioning

confidence: 99%