Angiolymphoid hyperplasia with eosinophilia successfully treated with imiquimod

Abstract

9 Viguier M, Rivet J, Agbalika F et al. B-cell lymphomas involving the skin associated with hepatitis C virus infection. Int J Dermatol 2002; 41: 577-82. 10 McKiernan S, Pilkington R, Ramsay B et al. Primary cutaneous B-cell lymphoma: an association of chronic hepatitis C infection. Eur J Gastroenterol Hepatol 1999; 11: 669-72.

A Long-Term Follow-Up of Angiolymphoid Hyperplasia with Eosinophilia Treated by Corticosteroids: When a Traditional Therapy is Still Up-to-Date

“…Continuous wave carbon dioxide and argon lasers have been successfully used, but there is a risk of scarring after treatment. Anecdotal reports have described other successful therapeutic options: intralesional interferon alpha-2a [7], indomethacin farnestil, pentoxifylline, chemotherapeutic agents such as vinblastine, mepolizumab (anti-interleukine-5) and imiquimod [8, 9]. Furthermore, oral retinoids have been employed with different results [2].…”

Angiolymphoid Hyperplasia with Eosinophilia Successfully Treated with Imiquimod

“…Most of these treatment methods are destructive, and recurrence has been reported in a part of the treated cases. Redondo et al [9] reported the first case of ALHE that obtained a complete clinical resolution with topical 5% imiquimod cream 5 times a week during 16 weeks without recurrence in the 4-month follow-up. We applied the imiquimod cream twice daily, for 5 days a week.…”

“…Cryotherapy, electrodesiccation, radiotherapy, intralesional steroid, retinoids, pentoxifylline, interferon α 2a , cytotoxic agents and laser treatment may also be a treatment choice [2, 9]. Most of these treatment methods are destructive, and recurrence has been reported in a part of the treated cases.…”

“…ALHE is a very rare benign vascular proliferation involving the head-neck region and especially the periauricular region mostly in middle-aged women without an obvious etiology [9]. Clinically, it is characterized by 1 or more pink or red-brown papules and nodules [9, 10].…”

“…Clinically, it is characterized by 1 or more pink or red-brown papules and nodules [9, 10]. Lesions tend to be solitary or multiple [1].…”