Angioleiomyoma of the Nasal Cavity

Arruda, Milena Moreira; Monteiro, Daniela; Fernandes, Atílio Maximino; Menegatti, Vanessa; Thomazzi, Emerson; Hubner, Ricardo Arthur; Lima, Luciana

doi:10.1055/s-0033-1364173

Cited by 14 publications

(8 citation statements)

References 9 publications

(27 reference statements)

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“…The initial literature search of the databases yielded a total of 366 articles. Of these articles, 40 met the inclusion criteria: 25 studies were single patient case reports, 5,7,12–34…”

Section: Resultsmentioning

confidence: 99%

Diagnosis, Treatment and Follow-Up of Sinonasal Leiomyomas: A Systematic Review

Runge

Randhawa

Mayo-Patiño

et al. 2023

Am J Rhinol�Allergy

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Background Leiomyomas are benign smooth muscle tumors that are rarely diagnosed in the nasal cavity and paranasal sinuses. Objective This systematic review summarizes the histopathologic and clinical tumor characteristics, surgical management, and follow-up of sinonasal leiomyomas. Methods A systematic review of the literature on sinonasal leiomyoma was performed by applying the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines. Studies that met the inclusion criteria were assessed for level of evidence. Patient demographics, clinical and pathological tumor characteristics, primary intervention, and results of follow-up were evaluated. Results Forty studies including 84 patients with sinonasal leiomyoma were identified. The tumor was most often located in the nasal cavity (47/84, 56%) originating from the inferior turbinate (32/84, 38%). Patients mostly presented with symptoms originating from an intranasal mass, including recurrent epistaxis (41/84, 49%), nasal obstruction (43/84, 51.2%), and localized facial or head pain (25/84, 29.8%). Surgery was performed in all cases. An endoscopic approach was most frequently chosen. Recurrence occurred only twice (2.4%). Morbidity was noted in 2 cases (2.4%) following postoperative bleeding and 1 (1.2%) case following a CSF leak. Conclusion Sinonasal leiomyomas are neoplasms of the smooth muscle manifesting clinically with recurrent epistaxis and nasal obstruction. Management goal is total resection with clear margins to avoid local recurrence.

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“…The initial literature search of the databases yielded a total of 366 articles. Of these articles, 40 met the inclusion criteria: 25 studies were single patient case reports, 5,7,12–34…”

Section: Resultsmentioning

confidence: 99%

Diagnosis, Treatment and Follow-Up of Sinonasal Leiomyomas: A Systematic Review

Runge

Randhawa

Mayo-Patiño

et al. 2023

Am J Rhinol�Allergy

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“…Some of the classic presenting symptoms include nasal obstruction (56.25%), epistaxis (56.25%), facial pain (25%), and headache (25%). 9 The preferred treatment for nasal septal angioleiomyoma is surgical excision resulting in clear margins. Complete removal of the mass is critical, because recurrence and malignant transformation have been reported.…”

Section: Discussionmentioning

confidence: 99%

“…Some of the classic presenting symptoms include nasal obstruction (56.25%), epistaxis (56.25%), facial pain (25%), and headache (25%). 9…”

Section: Discussionmentioning

confidence: 99%

Nasal Septal Angioleiomyoma and Septal Sinus Surgery: A Review of 2 Cases

2021

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Angioleiomyomas are smooth muscle masses originating from blood vessel tunica media. This is a rare tumor, comprising less than 1% of benign sinonasal cavity tumors. Failure to recognize and surgically excise nasal angioleiomyomas can result in lesion recurrence. We present 2 new cases of nasal septum angioleiomyoma at a single institution. Additionally, both cases underwent septal and nasal surgery. Due to the nonspecific clinical and imaging findings, a high index of suspicion is needed to diagnose nasal septum angioleiomyoma, often requiring histopathological verification. Preferred treatment is complete surgical excision. From our experience, concurrent corrective septal and sinus surgery can be completed with tumors less than 1.0 cm in size.

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“…Sinonasal lesions may be excised by endoscopic or open approach, using cold steel instruments, radiofrequency, or KTP laser [14]. We used the endoscopic two-hand technique to excise the lesion, including a cuff of surrounding mucosa using bipolar cautery.…”

Section: Discussionmentioning

confidence: 99%

Sinonasal Angioleiomyoma: A Rare Entity

Arora¹,

Mahindru²,

Kathuria³

2020

Biomed Hub

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The present case of angioleiomyoma of the nasal cavity in a 59-year-old male is unique, being the first case from North India and also because of its unique area of origin. The patient was referred to the Ear, Nose and Throat Outpatient Department with a diagnosis of an asymptomatic nasal mass. Biopsy done on the mass in another hospital reported angiofibroma. Excision was done after all relevant investigations. Histopathology revealed diagnosis of angioleiomyoma. Immunohistochemistry revealed desmin, SMA, and H-caldesmon positivity, consistent with the diagnosis of angioleiomyoma. Our case report thus highlights the importance of including this diagnosis in the differential diagnoses of nasal masses.

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Angioleiomyoma of the Nasal Cavity

Cited by 14 publications

References 9 publications

Diagnosis, Treatment and Follow-Up of Sinonasal Leiomyomas: A Systematic Review

Diagnosis, Treatment and Follow-Up of Sinonasal Leiomyomas: A Systematic Review

Nasal Septal Angioleiomyoma and Septal Sinus Surgery: A Review of 2 Cases

Sinonasal Angioleiomyoma: A Rare Entity

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