Angioinvasive aspergillosis with halo sign on computed tomography of the lungs

Fortes, Manuel; Meirelles, Gustavo de Souza Portes

doi:10.1590/s0037-86822008000200020

Cited by 3 publications

(1 citation statement)

References 3 publications

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“…Typical CT findings of early angioinvasive aspergillosis is solitary or multiple nodules and/or peripheral wedge-shaped consolidations with a surrounding halo of haemorrhage seen as an area of ground-glass attenuation (halo sign). With the progression of disease the nodules may cavitate and the central necrotic tissue detaches from the adjacent lung parenchyma resulting in the air crescent sign [38] . Nodule is defined as an ovoid soft-tissue opacity measuring < 3 cm in diameter.…”

Section: Airway Invasive Aspergillosis Is An Uncommon Invasive Diseasmentioning

confidence: 99%

An update of clinical characteristics and imaging findings of pulmonary aspergillosis

Sah

Liu

Ganganah

et al. 2015

IJDI

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Pulmonary aspergillosis (PA) is a clinical spectrum of rapidly progressive potentially fatal opportunistic mycosis usually caused by Aspergillus organisms. In the recent years, the number of patients with invasive pulmonary aspergillosis (IPA) has increased and it remains a major cause of morbidity and mortality in immunocompromised patients. Chest CT plays an important role in the early diagnosis of IPA and should be included in the investigative protocol. Typical imaging findings of IPA include nodule, consolidation, the halo sign, the hypodense sign and the air crescent sign. CT Angiography (CTA) has a higher sensitivity for detecting angioinvasive aspergillosis. However, the diagnosis of pulmonary aspergillosis remains challenging radiologically in immunocompetent chronic obstructive pulmonary disease (COPD) and critically ill patients in intensive care unit (ICU) because of the non-specific CT findings and further studies are needed to establish the confirm diagnosis.

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Section: Airway Invasive Aspergillosis Is An Uncommon Invasive Diseasmentioning

confidence: 99%

An update of clinical characteristics and imaging findings of pulmonary aspergillosis

Sah

Liu

Ganganah

et al. 2015

IJDI

View full text Add to dashboard Cite

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CT Halo sign: A systematic review

Goel

Mittal

Vyas

2020

European Journal of Radiology

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Histopathological Implications ofAspergillusInfection in Lung

Tochigi

Okubo

Ando

et al. 2013

Mediators of Inflammation

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This paper opens with a discussion on the significance of invasive fungal infections in advanced contemporary medicine, with an emphasis on the intractability of disease management and the difficulties of diagnosis. This is followed by a discussion concerning classification, histopathological features, and pathophysiology. While it has been largely accepted that Aspergillus species is recognized by cellular receptors and attacked by neutrophils, the radiological and macroscopic findings linking infection with neutropenia remain unconfirmed. In an effort to gain a better understanding of the pathophysiology and pathogenesis of invasive aspergillosis, we wish to emphasize the utility of radiological and histopathological examinations since these can provide detailed information on the extremely complex interaction between the causative microbes and tissue responses. A review of noninvasive or semi-invasive aspergillosis is also provided, with particular emphasis on chronic necrotizing pulmonary aspergillosis, which is recognized as a transition form of simple pulmonary aspergilloma and invasive pulmonary aspergillosis, although few findings have been reported in this area.

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Angioinvasive aspergillosis with halo sign on computed tomography of the lungs

Cited by 3 publications

References 3 publications

An update of clinical characteristics and imaging findings of pulmonary aspergillosis

An update of clinical characteristics and imaging findings of pulmonary aspergillosis

CT Halo sign: A systematic review

Histopathological Implications ofAspergillusInfection in Lung

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