2001
DOI: 10.1002/ccd.1230
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Angiographic prevalence and clinical predictors of left subclavian stenosis in patients undergoing diagnostic cardiac catheterization

Abstract: The angiographic prevalence, clinical predictors, and sensitivity and specificity of a bilateral arm blood pressure differential for predicting proximal left subclavian artery stenosis were established in 492 patients undergoing cardiac catheterization. Seventeen subjects (3.5%) in the overall population and nine subjects (5.3%) with potential surgical coronary disease had proximal left subclavian stenosis. Precatheterization evidence of peripheral vascular disease (PVD) was the only predictor of subclavian st… Show more

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Cited by 135 publications
(112 citation statements)
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References 15 publications
(18 reference statements)
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“…73 IAD prevalence is also high (78-88%) in subclavian steal syndrome, 74,75 and the severity of the stenosis has been associated with the size of the BP difference. 76 In another large series of patients presenting for coronary angiography, the non-simultaneously measured IAD had a low sensitivity and positive predictive value, but high specificity (85% for 410 mm Hg and 94% for X20 mm Hg) and negative predictive value (99% for 410 mm Hg and 98% for X20 mm Hg) for predicting subclavian stenosis, 77 and aortic arch angiography in a series of subjects with PVD showed a measurable stenosis of at least one brachiocephalic artery in 42% of 48 subjects studied. 78 Thus, there is evidence of an association of the IAD with symptomatic PVD.…”
Section: Pathophysiology Of the Iadmentioning
confidence: 99%
“…73 IAD prevalence is also high (78-88%) in subclavian steal syndrome, 74,75 and the severity of the stenosis has been associated with the size of the BP difference. 76 In another large series of patients presenting for coronary angiography, the non-simultaneously measured IAD had a low sensitivity and positive predictive value, but high specificity (85% for 410 mm Hg and 94% for X20 mm Hg) and negative predictive value (99% for 410 mm Hg and 98% for X20 mm Hg) for predicting subclavian stenosis, 77 and aortic arch angiography in a series of subjects with PVD showed a measurable stenosis of at least one brachiocephalic artery in 42% of 48 subjects studied. 78 Thus, there is evidence of an association of the IAD with symptomatic PVD.…”
Section: Pathophysiology Of the Iadmentioning
confidence: 99%
“…Data were separately analysed according to previously described cut off values for SBP differences of  10 and < 15 mmHg,  15 and < 20 mmHg or  20 mmHg. 9,10,11 An difference in SBP of <10 mmHg was considered an equal BP in both arms.…”
Section: Blood Pressure Measurementsmentioning
confidence: 99%
“…Atherosclerosis is the most common cause of this condition, but other etiologies include arteritis, inflammation due to radiation exposure, compression syndromes, fibromuscular dysplasia, and neurofibromatosis. The incidence of subclavian stenosis in the general population ranges from 3% to 4%, 1 and can be as high as 11-18% in patients with documented peripheral artery disease. 2 Of those patients found to have subclavian or innominate lesions, 50% have concomitant coronary artery disease, 27% lower extremity artery involvement and 29% carotid obstructive disease.…”
Section: Introductionmentioning
confidence: 99%