Angiographic and Clinical Outcomes in 200 Consecutive Patients with Cerebral Aneurysm Treated with Hydrogel-Coated Coils

Abstract

BACKGROUND AND PURPOSE:Denser coil packing in intracranial aneurysms is believed to result in lower recanalization rates. Hydrogel-coated expandable coils (HydroCoil) improve volumetric packing of aneurysms in animal models and clinical studies, but data from large clinical series are limited. The objective of this retrospective analysis was to analyze immediate and follow-up angiographic results as well as complications in a large consecutive series of patients treated with HydroCoils at a single institution.

HydroCoils, Occlusion Rates, and Outcomes: A Large Single-Center Study

“…The overall retreatment rate was 10.7%, though the average aneurysm size was quite large, 9.3 mm. 19 This increased propensity for recurrence in larger aneurysms has previously been proved in non-HydroCoil groups. 25,26 This is the largest reported HydroCoil patient group followed to date, and we have demonstrated a low rate of recurrence compared with the literature on coiling to date.…”

“…[9][10][11][12][13][14][15][16][17][18][19] These same articles were recently the subject of an evidence-based review of bioactive coils by White and Raymond,20 which revealed that on the evidence-based hierarchy, the published data were inadequate, only achieving a Cochrane level C. The downfall of many of these studies as described by the authors of this latter publication was the inaccurate and incomplete reporting of data. We have attempted to overcome some of the deficiencies highlighted by the way we have reported our data.…”

Embolization of Intracranial Aneurysms with HydroSoft Coils: Results of the Korean Multicenter Study

“…Table 6 summarizes some previous series with follow-up results reported in the literature. 14,[20][21][22] The major recanalization rate ranged from 7% to 20%. HydroCoils showed high initial aneurysmal occlusion rates and durability at the time of the follow-up evaluation.…”

Coil Type Does Not Affect Angiographic Follow-Up Outcomes of Cerebral Aneurysm Coiling: A Systematic Review and Meta-Analysis

“…1 In an effort to improve long-term occlusion rates, a number of "modified," second-generation coil types have been developed and marketed. Numerous single-center case series have been published regarding outcomes for each of these second-generation coil types, including Matrix (Boston Scientific, Natick, Massachusetts), [2][3][4] HydroCoil (MicroVention, Tustin, California), [5][6][7] and Cerecyte coils (Codman Neurovascular, Raynham, Massachusetts). 8,9 In addition, outcomes from several randomized, controlled trials (RCTs) of the major coil types have recently been reported.…”