Angiographic and clinical outcomes following acute infarct angioplasty on saphenous vein grafts

Misguided Use of Multivariable Analysis to Study Primary Percutaneous Coronary Intervention in Patients With Prior Coronary Artery Bypass Graft

“…13,14 Both reports are notable for the large number of patients with prior CABG and the documentation of higher unadjusted mortality rates in patients with prior CABG, confirming observations from the smaller earlier reports [4][5][6][7][8][9][10][11][12] and clinical experience. The major limitation with both reports is selection bias that excluded patients with ST-segment-elevation myocardial infarction and prior CABG who either were not referred for emergency coronary 2…”

“…2,3 Similarly, primary PCI in SVBGs with balloon angioplasty or stent implantation has lower successful reperfusion rates, lower long-term patency rates, and higher complication rates, including death than in native coronary arteries. [4][5][6][7][8][9][10][11][12] No additional SVBG reperfusion benefit has been gained with intragraft fibrinolytic therapy, intravenous platelet glycoprotein IIb/IIIa inhibitors, mechanical or aspiration thrombectomy, or distal embolic protection devices.…”

Initial thrombosuction with subsequent angioplasty in primary coronary intervention—comparison with conventional strategy

“…The mechanisms may be gruel dissemination from the disrupted plaque/thrombi and microthromboemboli formation, leading to distal embolism and failed actual perfusion at myocardial level [15,16]. Noreflow was reported in 13-70% of primary PCI [10,17] and predicted more adverse clinical outcome [18].…”

Cytokeratin 8 in venous grafts: A factor of unfavorable long-term prognosis in coronary artery bypass grafting patients

“…Secondary to locally distributed stimulating agents, they are able to migrate through internal elastic lamina to tunica intima, proliferate and secrete extracellular matrix [7]. It results in progressive neointimal formation that might lead to the decisive narrowing of the grafts and clinically CAD progression or angina recurrence and, in some cases, acute coronary syndromes (ACSs) [8].…”