Angiogenic activity of mitochondria; beyond the sole bioenergetic organelle
Fatemeh Sadeghsoltani,
Parisa Hassanpour,
Mir‑Meghdad Safari
et al.
Abstract:Angiogenesis is a complex process that involves the expansion of the pre‐existing vascular plexus to enhance oxygen and nutrient delivery and is stimulated by various factors, including hypoxia. Since the process of angiogenesis requires a lot of energy, mitochondria play an important role in regulating and promoting this phenomenon. Besides their roles as an oxidative metabolism base, mitochondria are potential bioenergetics organelles to maintain cellular homeostasis via sensing alteration in oxygen levels. … Show more
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