2019
DOI: 10.3390/ijms20153728
|View full text |Cite
|
Sign up to set email alerts
|

Angiogenesis, Lymphangiogenesis, and the Immune Response in South African Preeclamptic Women Receiving HAART

Abstract: Purpose of the review: This review highlights the role of angiogenesis, lymphangiogenesis, and immune markers in human immunodeficiency virus (HIV)-associated preeclamptic (PE) pregnancies in an attempt to unravel the mysteries underlying the duality of both conditions in South Africa. Recent findings: Studies demonstrate that HIV-infected pregnant women develop PE at a lower frequency than uninfected women. In contrast, women receiving highly active anti-retroviral therapy (HAART) are more inclined to develop… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
1

Citation Types

0
7
0

Year Published

2020
2020
2023
2023

Publication Types

Select...
10

Relationship

4
6

Authors

Journals

citations
Cited by 11 publications
(7 citation statements)
references
References 126 publications
(144 reference statements)
0
7
0
Order By: Relevance
“…Endothelial survival, proliferation, and migration are the main factors for angiogenic stimulation through increased soluble factor mediation (Demidova-Rice et al, 2012). The process of angiogenesis occurs because it begins with the initiation of Vascular Endothelial Growth Factors (VEGFs) and Placental Growth Factors (PlGFs) (Naicker et al, 2019). Pathology of female reproductive organs also affects the occurrence of angiogenesis disorders (Reynolds et al, 2002).…”
Section: Angiogenesismentioning
confidence: 99%
“…Endothelial survival, proliferation, and migration are the main factors for angiogenic stimulation through increased soluble factor mediation (Demidova-Rice et al, 2012). The process of angiogenesis occurs because it begins with the initiation of Vascular Endothelial Growth Factors (VEGFs) and Placental Growth Factors (PlGFs) (Naicker et al, 2019). Pathology of female reproductive organs also affects the occurrence of angiogenesis disorders (Reynolds et al, 2002).…”
Section: Angiogenesismentioning
confidence: 99%
“…Also, ART may cause direct endothelial injury and promote endothelial dysfunction [ 26 ], which is an important risk factor for CVDs. Although ART and HIV have been associated with CVDs, such findings are yet to be established in HIV pregnant women [ 27 , 28 ].…”
Section: Introductionmentioning
confidence: 99%
“…In South Africa, PE affects about 5% of pregnant women and 12% of primigravidae (14,15). Although the cause(s) of PE remain unclear, it is thought to stem from placental malfunction during pregnancy (16) resulting in foetal hypo-perfusion associated with oxidative stress and low-grade inflammation (17)(18)(19).…”
Section: Introductionmentioning
confidence: 99%