Angelica archangelica Linn. is an angel on earth for the treatment of diseases

Bhat, Zulfiqar Ali; Kumar, Dinesh; Shah, M. Y.

doi:10.4103/2231-0738.77531

Cited by 29 publications

(4 citation statements)

References 2 publications

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“…The differences may be due to the different preparation of the extract, the part of the plant material used and its origin and time of harvest. Angelica archangelica is a member of the Apiaceae family and all parts of the plant can be used for pharmacological and food purposes, as well as in traditional and folk medicine as a remedy for fever, skin rashes or bronchitis [19,35]. However, in the root and fruit extracts of A. purpurascens, almost twice as high a TPC content as in extracts from the aerial part was observed [36].…”

Section: Extraction Yield and Total Phenolics Content (Tpc)mentioning

confidence: 99%

“…Angelica archangelica L. (Apiaceae), a valuable medicinal plant that has been partially protected in Poland since 2014, is characterized by its peculiar and pleasant fragrance. The stems and seeds are used in confectionery and in the preparation of liqueurs, and the leaves and roots for medicinal purposes, especially in digestive problems, anorexia, migraine or menstrual and obstetric complaints [19]. The roots are a source of coumarins, a flavonoid called archangelenone, palmitic acid and sugar [20].…”

Section: Introductionmentioning

confidence: 99%

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Antioxidant and Antibacterial Activity of Extracts from Selected Plant Material

et al. 2022

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Plants are a valuable source of biologically active molecules, mainly phenolic compounds. In the present study, the total phenolic content (TPC), DPPH· and ABTS+ scavenging activity as well as ferric reducing ability (FRAP) of aqueous ethanolic (70%) extracts of Cistus incanus L. and Asarum europaeum L. herb, Geum urbanum L. rhizome, Angelica archangelica L. root, white mulberry (Morus alba L.), lemon balm (Melisa officinalis L.), red raspberry (Rubus idaeus L.) and Betula pendula Roth. leaves were determined. In addition, the phenolic profiles of the studied plant extracts and antibacterial activity have been investigated. The extracts from C. incanus and G. urbanum demonstrated the highest TPC and antioxidant capacity, while the extracts from A. archangelica and white mulberry were characterized by the lowest values. A remarkable correlation was also found between the TPC and antioxidant activity of the examined extracts. HPLC analysis showed that the studied extracts were sources of both phenolic acids and flavonoids. More flavonoids than phenolic acids were identified in the extracts of C. incanus, M. alba, R. idaeus and B. pendula compared to the other extracts tested. Not all extracts showed a significant impact on the growth of the tested bacterial strains. Escherichia coli was the most sensitive strain to lemon balm extract (MIC, 0.125 mg/mL), whereas the strains of Acinetobacter baumannii and Bordetella bronchiseptica were sensitive to the G. urbanum extract (MIC, 0.125 mg/mL). Among Gram-positive bacteria, Enterococcus faecalis was the most sensitive to G. urbanum extract. In turn, Staphylococcus aureus and Staphylococcus epidermidis were sensitive to the extracts from C. incanus herb (MIC, 0.125 mg/mL), red raspberry (MIC, 0.125 mg/mL) and lemon balm leaves (MIC. 0.25 mg/mL). Based on the obtained results, the applicability of the studied plant extracts as additives to food and cosmetic products may be considered in the future.

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Section: Extraction Yield and Total Phenolics Content (Tpc)mentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Antioxidant and Antibacterial Activity of Extracts from Selected Plant Material

et al. 2022

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“…Due to its unaccountable remedial properties, A . archangelica is also considered as an “Angel plant” in the traditional medicine system (Bhat et al, 2011). Phytochemical investigations on A .…”

Section: Angelica Archangelicamentioning

confidence: 99%

“…A. archangelica, commonly known as wild celery, is a potent food supplement and the whole plant parts are used in traditional medicine (Chandra & Saklani, 2017). Due to its unaccountable remedial properties, A. archangelica is also considered as an "Angel plant" in the traditional medicine system (Bhat et al, 2011). Phytochemical investigations on A.…”

Section: Angelica Archangelicamentioning

confidence: 99%

A comprehensive review of antitumor properties of Angelica species and their antitumor‐responsible constituents and the underlying molecular mechanisms involved in tumor inhibition

Sabeel

Liang

Hao

et al. 2023

Phytotherapy Research

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Angelica species have been traditionally used for their medicinal properties. Recent studies have suggested their potential use as anticancer agents, making them an area of interest for further research. The review aims to summarize the current understanding of the potential anticancer effects of Angelica species and to provide insights for further research in this area. We searched for “Angelica” related information on Google Scholar, PubMed, ScienceDirect, Wiley, Science Citation Index Finder, and Springer link by searching keywords such as “Angelica,” “Angelica phytochemical,” “Angelica antitumor effect,” “Angelica molecular mechanisms,” and “Angelica clinical application.” Included articles focused on the Angelica plant's anticancer properties and clinical studies, while non‐cancer‐related biological or phytochemical investigations were excluded. We conducted a comprehensive search of books, journals, and databases published between 2001 and 2023, identifying 186 articles for this narrative review. The articles were analyzed for their potential anticancer properties and therapeutic applications. Active compounds in the Angelica genus, such as coumarins, furanocoumarins, phthalides, and polysaccharides, exhibit anticancer properties through various mechanisms. Specific species, like A. archangelica, Angelica sinensis, A. gigas, and A. ksiekie, have the potential as anticancer agents by targeting cellular pathways, generating reactive oxygen species, and inducing apoptotic cell death. Further research into the properties of the Angelica genus is needed for developing new treatments for cancer. Phytochemicals from Angelica species possess potential as anticancer agents, requiring further research for the development of effective, low‐cost, and low‐toxicity cancer treatments compared to synthetic antitumor drugs.

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Understanding the phytochemistry and molecular insights to the pharmacology of Angelica archangelica L. (garden angelica) and its bioactive components

Kaur

Bhatti

2021

Phytotherapy Research

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Plant-derived molecules have enduring usefulness in treating diseases, and herbal drugs have emerged as a vital component of global therapeutic demand. Angelica archangelica L. (A. archangelica), commonly known as garden angelica, is an aromatic food plant used in culinary procedures as a flavoring agent. In the traditional medicine system, it is regarded as an "Angel plant" due to its miraculous curative power. This review aims to provide a comprehensive summary of the plant's taxonomic profile, ethnopharmacology, Phytochemistry, and pharmacological activities. Various in vivo and in vitro experiments have validated that the plant possesses broad pharmacological potential. The biological activities attributed to the plant include anti-anxiety activity, anti-convulsant activity, cognition enhancer, antiviral activity, cholinesterase inhibitory potential, antiinflammatory activity, gastroprotective activity, and radioprotective activity. The beneficial effects of the plant are credited to its bioactive components, that is, coumarins and volatile oils. The review summarizes the pharmacological activities of crude extract and its bioactive fractions and has also explored their target-oriented effects. This review will be of value in undertaking further investigations on the plant with regard to exploring mechanism-based pharmacological approaches on A. archangelica.

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Angelica archangelica Linn. is an angel on earth for the treatment of diseases

Cited by 29 publications

References 2 publications

Antioxidant and Antibacterial Activity of Extracts from Selected Plant Material

Antioxidant and Antibacterial Activity of Extracts from Selected Plant Material

A comprehensive review of antitumor properties of Angelica species and their antitumor‐responsible constituents and the underlying molecular mechanisms involved in tumor inhibition

Understanding the phytochemistry and molecular insights to the pharmacology of Angelica archangelica L. (garden angelica) and its bioactive components

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