Aneurysmal Bone Cyst Secondary to Other Osseous Lesions: Report of 57 Cases

Abstract

Fifty-seven aneurysmal bone cysts which were associated with or secondary to other lesions of bone are reported. The most common associations were with solitary or unicameral bone cyst, and with osteoclastoma. Other associated lesions included osteosarcoma, nonosteogenic fibroma, osteoblastoma, hemangioendothelioma, and hemangioma of bone. Five aneurysmal bone cysts were secondary to fracture or other bone trauma.

Hip Salvageable Surgery for an Extensive Aneurysmal Bone Cyst Complicated with Transcervical Neck of Femur Fracture

“…They may also arise in conjunction with other lesions like fibrous dysplasia, osteoblastoma, chondromyxoid fibroma, nonossifying fibroma, chondroblastoma, osteosarcoma, chondrosarcoma, unicameral bone cyst, hemangioendothelioma, and metastatic carcinoma. Such tumours are designated as 'Secondary ABCs' [11]. Features of the current case were consistent with primary ABC.…”

Occipital Aneurysmal Bone Cyst Secondary to Eosinophilic Granuloma

“…Secondary examples may occur in any site, depending on precursor lesions. The most common precursors are giant cell tumor, osteoblastoma, angioma and chondroblastoma [2, 3, 4]. Rarely, ABC occurs secondary to giant cell reparative granuloma, fibrous dysplasia, osteosarcoma, fibroxanthoma, solitary bone cyst, fibrous histiocytoma and eosinophilic granuloma (EG) [2, 3, 4, 5].…”

A 16-year-old Girl With Pain and Swelling in the Medial Clavicle

“…The presence of a secondary aneurysmal bone cyst component can lead to a more aggressive clinical and radiographic appearance [8,9]. Often patients with an aneurysmal bone cyst present with pain and swelling, in contrast to the subtle clinical presentation of nonossifying fibroma [9,10]. The extent of aneurysmal change grossly and histologically in this case was minimal; however, it may account for the more aggressive clinical and radiographic appearance of the tumor.…”

“…Giant cells and lipid-laden histiocytes are present in an irregular distribution [4]. Secondary aneurysmal bone cyst formation has been reported in a variety of benign bone tumors; however, it is not a common finding in nonossifying fibroma [7][8][9][10]. Grossly, a hemorrhagic cavitary expansion is usually present.…”

“…Microscopically, blood-filled cystic areas are seen with fibrous lining, macrophages, and giant cells. The presence of a secondary aneurysmal bone cyst component can lead to a more aggressive clinical and radiographic appearance [8,9]. Often patients with an aneurysmal bone cyst present with pain and swelling, in contrast to the subtle clinical presentation of nonossifying fibroma [9,10].…”