Aneurysmal Bone Cyst Recurrence in Children

Başarır, Kerem; Pişkin, Ahmet; Güçlü, Berk; Yıldız, Yusuf; Sağlık, Yener

doi:10.1097/bpo.0b013e31815a5fd3

Cited by 80 publications

(67 citation statements)

References 26 publications

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“…Adjuvant radiation therapy is associated with excellent control of ABCs, ranging from 83 to 100 % local control [22,24,26,29,45]. However, complications from radiotherapy include chronic effects that can impair function and secondary malignancies, which have prevented its adoption into widespread practice.…”

Section: Adjuvant Radiotherapymentioning

confidence: 99%

Current management of aneurysmal bone cysts

Park

Yang

Sheppard

et al. 2016

Curr Rev Musculoskelet Med

184

259

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Aneurysmal bone cysts (ABCs) are benign bone lesions arising predominantly in the pediatric population that can cause local pain, swelling, and pathologic fracture. Primary lesions, which constitute roughly two thirds of all ABCs, are thought to be neoplastic in nature, with one third of ABCs arising secondary to other tumors. Diagnosis is made with various imaging modalities, which exhibit characteristic features such as Bfluid-fluid levels,^although biopsy is critical, as telangiectatic osteosarcoma cannot be excluded based on imaging alone. Currently, the standard of care and most widely employed treatment is intralesional curettage. However, tumor recurrence with curettage alone is common and has driven some to propose a multitude of adjuvants with varying efficacy and risk profiles. Historically, therapies such as en bloc resection or radiation therapy were utilized as an alternative to decrease the recurrence rate, but these therapies imposed high morbidity. As a result, modern techniques now seek to simultaneously reduce morbidity and recurrence, the pursuit of which has produced preliminary study into minimally invasive percutaneous treatments and medical management.

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Section: Adjuvant Radiotherapymentioning

confidence: 99%

Current management of aneurysmal bone cysts

Park

Yang

Sheppard

et al. 2016

Curr Rev Musculoskelet Med

184

259

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“…[12][13][14][15][16][17][18][19][20][21] En nuestra serie, hemos encontrado una relación con significancia estadística úni-camente entre QOA con contacto fisario y recidiva. A su vez, observamos mayores tasas de recidiva en pacientes de sexo femenino (45% frente al 28% en el sexo masculino), y en pacientes <10 años de edad; en estos casos, no se logró la significancia estadística, probablemente por el escaso tamaño de la muestra.…”

Section: Discussionunclassified

Tratamiento de quistes óseos aneurismáticos con aloinjerto. [Treatment of aneurysmal bone cysts with allograft.]

Nùñez

Chelle²,

Fajardo³

et al. 2016

Rev. Asoc. Arg. Ort. y Traumatol

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ResumenAntecedentes: Los pacientes con quiste óseo aneurismático plantean dificultades diagnósticas y terapéuticas. Se han descrito múltiples opciones terapéuticas. Objetivos: Evaluar los resultados obtenidos en pacientes tratados con curetaje y relleno con aloinjerto óseo. Materiales y Métodos: Se analizaron 16 quistes, correspondientes a 15 pacientes, con un seguimiento mínimo de 28 meses y una mediana de seguimiento de 83 meses. Resultados: La media de la edad era de 10 años (rango 3-16). La principal complicación fue la recidiva (37,5%), que fue más frecuente cuando existía compromiso fisario (62,5% frente al 12,5% sin compromiso; p = 0,05). La frecuencia de recidiva no varió en ambos sexos, para las distintas edades analizadas y respecto al uso o no de fresa de alta velocidad. Conclusión: Consideramos que el tratamiento realizado es seguro, pero tiene una alta tasa de recidivas, similar a las publicadas en otras series.Palabras clave: Quiste óseo aneurismático; aloinjerto. Nivel de Evidencia: IV Treatment of aneurysmal bone cysts with allograft AbstractBackround: Patients with aneurysmal bone cyst pose diagnostic and therapeutic difficulties. Multiple therapeutic options have been described. Objective: To evaluate the results obtained in patients treated with curettage and filling with bone allograft. Methods: Sixteen cysts, corresponding to 15 patients were evaluated, with a minimum follow-up of 28 months and a median follow-up of 83 months. Results: Average age was 10 years (range 3-16). The main complication was recurrence in 37.5% of patients, being more frequent with physeal involvement (62.5% vs. 12.5% without involvement; p = 0.05). The recurrence rate was unchanged for both sexes, for different ages and regarding the use or not of high-speed burr. Conclusion: We think that the treatment performed is safe, but recurrence rate is high, similar to that reported in other series.

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“…Total patellectomy or a patellar prosthesis is recommended for aggressive lesions that disrupt the patellar articular surface [10,13]. Recurrence rates after curettage vary widely from 9% to 71%, with lesions of the humerus and femur most common [1,4]. Some authors have reported higher recurrence rates with aneurysmal bone cysts in children younger than 15 years [20].…”

Section: Discussion and Treatmentmentioning

confidence: 99%

An 11-year-old Boy with a Patella Fracture

Nydick

Herman

Chadarévian

2009

Clin Orthop Relat Res

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An 11-year old boy presented to the pediatric emergency department with left knee pain after tripping in the school yard and striking his knee on concrete. He denied having left knee pain before his fall. There was no history of recent skin or other infections, fever, or constitutional symptoms or signs. His medical history and family history were noncontributory.On physical examination, his skin was intact except for a small superficial abrasion over his left patella. A small knee effusion was present and the patella was tender to palpation. He was able to actively extend the knee, but flexion was painful and limited to 30°. The remainder of the physical examination was unremarkable. Radiographs were interpreted as showing a minimally displaced transverse patella fracture (Fig. 1). He wore a cylinder cast for 6 weeks and radiographs were obtained after cast removal (Fig. 2). Three months after cast removal, he was prescribed physical therapy for persistent quadriceps weakness. This consisted of quadriceps strengthening, active assisted knee range of motion, and activity as tolerated. When seen 8 months after injury for routine followup, he had normal knee motion but complained of pain with maximal knee flexion and prolonged walking.Radiographs were repeated 8 months after injury (Fig. 3) and the prior radiographs were rereviewed. MRI of the knee was performed 10 months after injury (Fig. 4). Complete blood count, erythrocyte sedimentation rate, and C-reactive protein were normal.Based on the history, physical examination, and imaging studies, what is the differential diagnosis?Imaging Interpretation

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Aneurysmal Bone Cyst Recurrence in Children

Cited by 80 publications

References 26 publications

Current management of aneurysmal bone cysts

Current management of aneurysmal bone cysts

Tratamiento de quistes óseos aneurismáticos con aloinjerto. [Treatment of aneurysmal bone cysts with allograft.]

An 11-year-old Boy with a Patella Fracture

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