Aneurysm of the Pulmonary Artery, a Systematic Review and Critical Analysis of Current Literature

Duijnhouwer, Anthonie L.; Navarese, Eliano Pio; Dijk, Arie P.J. van; Loeys, Bart; Roos‐Hesselink, Jolien W.; Boer, Menko Jan de

doi:10.1111/chd.12316

Cited by 70 publications

(90 citation statements)

References 31 publications

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“…In our case, there was a left‐to‐right PDA shunt, with high‐speed hitting of the wall of the PA causing local injury and arterial wall weakness. Approximately 81% of patients with PAA have pulmonary arterial hypertension, which has been suggested as a contributing factor to the development of PAA . The left‐to‐right shunt can increase PA pressure.…”

Section: Discussionmentioning

confidence: 99%

“…Even nowadays, increasing tuberculosis in some countries remains the main pathogenic factors of PAA . Several bacteria and fungi are less commonly factors of PAA including S. aureus , Streptococcus spp, Corynebacterium diphtheriae , Candida albicans , and Aspergillus flavus . Blood cultures with S. aureus increase the risk of a mycotic aneurysm.…”

Section: Discussionmentioning

confidence: 99%

“…10 Several bacteria and fungi are less commonly factors of PAA including S. aureus, Streptococcus spp, Corynebacterium diphtheriae, Candida albicans, and Aspergillus flavus. 7,11,12 Blood cultures with S. aureus increase the risk of a mycotic aneurysm. In a vessel wall already under stress, septic emboli can lodge and cause aneurysmal formation.…”

Section: A S E Rep Ortmentioning

confidence: 99%

“…Approximately 81% of patients with PAA have pulmonary arterial hypertension, 5 which has been suggested as a contributing factor to the development of PAA. 6,7 The left-to-right shunt can increase PA pressure. Similar to previous reports, 8 PDA and mild pulmonary arterial hypertension were identified by echocardiography in our case.…”

Section: Introductionmentioning

confidence: 99%

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Pulmonary artery aneurysm secondary to patent arterial duct and infection: A case report and review

Zhang

et al. 2018

Echocardiography

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Pulmonary artery aneurysms (PAAs) are very rare condition. In this paper, we report a case of a twenty‐year‐old female patient with the aneurysm of the pulmonary trunk secondary to the patent arterial duct (PDA) and infection. Diagnosis of PAA was confirmed by echocardiography. The pulmonary artery computed tomographic angiography also revealed the aneurysm and drawn a similar conclusion as echo did. The patient underwent surgery of ligation of PDA and PAA aneurysmectomy repairing with pericardium graft.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: A S E Rep Ortmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Pulmonary artery aneurysm secondary to patent arterial duct and infection: A case report and review

Zhang

et al. 2018

Echocardiography

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“…Indeed, the detection of a dilated PA often leads to the diagnosis of PAH [2]. Pulmonary artery aneurysm (PAA) is defined as a main PA dilatation above 40 mm diameter [3][4][5] and has been classically diagnosed in post-mortem studies [6]. However, in recent years its detection has increased [3].…”

Section: Introductionmentioning

confidence: 99%

Potential Molecular Pathways Related to Pulmonary Artery Aneurysm Development: Lessons to Learn from the Aorta

Nuche

Palomino-Doza

Arribas

et al. 2020

IJMS

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Pulmonary arterial hypertension (PAH) is a rare disease caused by pulmonary vascular remodeling. Current vasodilator treatments have substantially improved patients' survival. This improved survival has led to the appearance of complications related to conditions previously underdiagnosed or even ignored, such as pulmonary artery aneurysm (PAA). The presence of a dilated pulmonary artery has been shown to be related to an increased risk of sudden cardiac death among PAH patients. This increased risk could be associated to the development of left main coronary artery compression or pulmonary artery dissection. Nevertheless, very little is currently known about the molecular mechanisms related to PAA. Thoracic aortic aneurysm (TAA) is a well-known condition with an increased risk of sudden death caused by acute aortic dissection. TAA may be secondary to chronic exposure to classic cardiovascular risk factors. In addition, a number of genetic variants have been shown to be related to a marked risk of TAA and dissection as part of multisystemic syndromes or isolated familial TAA. The molecular pathways implied in the development of TAA have been widely studied and described. Many of these molecular pathways are involved in the pathogenesis of PAH and could be involved in PAA. This review aims to describe all these common pathways to open new research lines that could help lead to a better understanding of the pathophysiology of PAH and PAA and their clinical implications.

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Women with sudden cardiac arrest

Wang

Chen

2021

JACEP Open

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Aneurysm of the Pulmonary Artery, a Systematic Review and Critical Analysis of Current Literature

Abstract: High-risk PA aneurysms maybe identified by evaluating: the causative mechanism(s) for PA dilatation, absolute PA diameter and growth rate and by evaluating the PA systolic pressure.

Cited by 70 publications

References 31 publications

Pulmonary artery aneurysm secondary to patent arterial duct and infection: A case report and review

Pulmonary artery aneurysm secondary to patent arterial duct and infection: A case report and review

Potential Molecular Pathways Related to Pulmonary Artery Aneurysm Development: Lessons to Learn from the Aorta

Women with sudden cardiac arrest

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