Aneurisma de arteria mamaria interna en paciente con displasia fibromuscular

Coil embolization of bilateral internal mammary artery aneurysms in the setting of a heterozygous missense variant of unknown significance in COL5A1 and fibromuscular dysplasia

“…Noniatrogenic cases have been attributed to connective tissue disorders including Marfan, Ehlers-Danlos, Loeys-Dietz, and SMAD3 mutation syndromes; in addition to other systemic vascular disorders including polyarteritis nodosa, FMD, and atherosclerosis. Only one other case of internal mammary artery aneurysm in a patient with FMD has previously been reported; and no treatment was undertaken in that report 11 . Presented here is an extremely rare case of bilateral internal mammary artery aneurysms in a 62-year-old man with angiographic evidence of multifocal FMD, as well as heterozygosity for a missense variant in COL5A1—a gene implicated in Ehlers-Danlos syndrome with type V collagenopathy.…”

“…The majority of published reports describe iatrogenic or traumatic pseudoaneurysms 1 . Only 14 cases to date have described noniatrogenic internal mammary artery aneurysms caused by vasculitides, connective tissue disorders, and rarely idiopathic etiology 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14. Bilateral internal mammary artery aneurysms are even less common, with only two published reports, both describing patients with Marfan syndrome 6, 9…”