ANet: Autoencoder-Based Local Field Potential Feature Extractor for Evaluating An Antidepressant Effect in Mice after Administering Kratom Leaf Extracts
Abstract:Kratom (KT) typically exerts antidepressant (AD) effects. However, evaluating which form of KT extracts possesses AD properties similar to the standard AD fluoxetine (flu) remained challenging. Here, we adopted an autoencoder (AE)based anomaly detector called ANet to measure the similarity of mice's local field potential (LFP) features that responded to KT leave extracts and AD flu. The features that responded to KT syrup had the highest similarity to those that responded to the AD flu at 85.62 ± 0.29%. This f… Show more
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