Anesthetic effect of propofol combined with remifentanil or sevoflurane anesthesia on patients undergoing radical gastrectomy

Feng, Yazhen; Ji, Li; Wang, Hushan; Duan, Zongsheng

doi:10.3892/ol.2019.10238

Cited by 5 publications

(4 citation statements)

References 23 publications

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“…These results suggested that compared with propofol alone, sevoflurane combined with propofol can improve the recovery quality from anesthesia, which is consistent with previous reports. 19 Meanwhile, in our study, the HR levels of the two groups immediately after intubation and during exploration were significantly higher than those at the time of entering the room. While the level in the observation group was lower than that of the control group, with statistically significant difference, and there was no significant difference at other time points compared with that at the time of entering the room and the control group.…”

Section: A H E a D O F P R I N Tcontrasting

confidence: 39%

Effects of intravenous anesthesia with sevoflurane combined with propofol on intraoperative hemodynamics, postoperative stress disorder and cognitive function in elderly patients undergoing laparoscopic surgery

Yang¹,

Chen²,

Dengguo

2022

Pak J Med Sci

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Objectives: To analyze the effects of intravenous anesthesia with sevoflurane combined with propofol on intraoperative hemodynamics, postoperative stress disorder and cognitive function in elderly patients undergoing laparoscopic surgery. Methods: Eighty elderly patients undergoing laparoscopic surgery in Xianning Central Hospital from September 2014 to February 2018. Enrolled patients were divided into observation group (n=40) and control group (n=40) according to the random regionalization method. Patients in the control group were given intravenous anesthesia with propofol, while those in the observation group were provided with a combined use of sevoflurane based on the method in the control group. The general surgical data, intraoperative hemodynamics, postoperative stress disorder and cognitive function were compared between the two groups. Results: There were no blood transfusions and no complications during operation in the two groups, and the operation completed successfully. There was no significant difference in the time of unconsciousness, intubation time, and duration of pneumoperitoneum establishment (p>0.05). However, the spontaneous breathing time, eye opening time upon calling and extubation time in observation group were shorter than those in control group (p<0.05). The heart rate (HR) in the two groups at intubation and at exploration was significantly higher than that at the time of entering the room (p<0.05), which was lower in observation group than that in control group (p<0.05). While there was no significant difference in the index at the other time points compared with that before entering the room and control group (p>0.05). The systolic blood pressure (SBP) had different degrees of change before intubation, after 0 minutes, three minutes and six minutes of intubation, after 0 minutes and five minutes of pneumoperitoneum establishment and at exploration when compared with that before entering the room (p<0.05). But the SBP at intubation and at exploration was significantly lower in observation group than that in control group (p<0.05). MAP was only decreased significantly at intubation compared with that before entering the room (p<0.05). At exploration, there was no significant fluctuation in the MAP level in observation group (p>0.05), but the MAP was increased significantly in control group (p<0.05). In addition, the postoperative stress disorder in observation group was milder than that in control group (p<0.05), and the postoperative cognitive function was better than that in control group (p<0.05). Conclusions: Intravenous anesthesia with sevoflurane combined with propofol has little effects on intraoperative hemodynamics and postoperative cognitive function in elderly patients undergoing laparoscopic surgery. Besides, it can obtain better recovery quality and have milder postoperative stress disorder than single use of propofol. doi: https://doi.org/10.12669/pjms.38.7.5763 How to cite this:Yang L, Chen Z, Xiang D. Effects of intravenous anesthesia with sevoflurane combined with propofol on intraoperative hemodynamics, postoperative stress disorder and cognitive function in elderly patients undergoing laparoscopic surgery. Pak J Med Sci. 2022;38(7):---------. doi: https://doi.org/10.12669/pjms.38.7.5763 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Section: A H E a D O F P R I N Tcontrasting

confidence: 39%

Effects of intravenous anesthesia with sevoflurane combined with propofol on intraoperative hemodynamics, postoperative stress disorder and cognitive function in elderly patients undergoing laparoscopic surgery

Yang¹,

Chen²,

Dengguo

2022

Pak J Med Sci

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“…It has been frequently reported that propofol can reduce the incidence of emergence agitation in children undergoing sevoflurane anesthesia 18 . The results of Feng et al 19 . showed that patients undergoing radical gastrectomy with the combination of sevoflurane and propofol had stable respiration and circulation during anesthesia, quick recovery of early consciousness and a low incidence of adverse reactions.…”

Section: Discussionmentioning

confidence: 99%

“…18 It has been frequently reported that propofol can reduce the incidence of emergence agitation in children undergoing sevoflurane anesthesia. 18 The results of Feng et al 19 showed that patients undergoing radical gastrectomy with the combination of sevoflurane and propofol had stable respiration and circulation during anesthesia, quick recovery of early consciousness and a low incidence of adverse reactions. The data presented by Sebel et al 17 showed propofol and sevoflurane to modulate GABA receptor function and generate the anesthetized state in an additive manner, and with good sedation effects.…”

Section: Discussionmentioning

confidence: 99%

Comparison of hemodynamic changes with general or local anesthesia during dental treatment in pediatric patients: A prospective clinical study

Pérez‐García,

Acosta‐Ibarra,

Ruiz‐Roca

et al. 2023

Special Care in Dentistry

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Background and aimSevere hemodynamic fluctuations during dental treatment can trigger highly undesirable physical reactions. A study was made to determine whether the administration of propofol and sevoflurane contributes to the stabilization of hemodynamic parameters during dental treatment in pediatric patients versus the use of local anesthesia alone.Materials and methodsForty pediatric patients needing dental treatment were assigned to either general anesthesia with local anesthesia (study group [SG]) or local anesthesia alone (control group [CG]). Two percent sevoflurane in oxygen (100% oxygen, 5 L/min) and continuous propofol infusion (target‐controlled infusion [TCI], 2 μg/mL) were used as general anesthesia agents in SG; and 2% lidocaine with 1:80,000 adrenaline was used as local anesthesia in both groups. Heart rate, blood pressure and oxygen saturation were measured before starting dental treatment (baseline) and every 10 min during dental treatment.ResultsBlood pressure (p < .001), heart rate (p = .021) and oxygen saturation (p = .007) decreased substantially after the administration of general anesthesia. The levels of these parameters subsequently remained low and then recovered at the end of the procedure. On the other hand, the oxygen saturation values remained closer to baseline in SG versus CG. In contrast, the hemodynamic parameters experienced lesser fluctuations in CG than in SG.ConclusionsGeneral anesthesia affords more favorable cardiovascular parameters during the entire dental treatment in comparison to local anesthesia alone (blood pressure and heart rate decrease significantly and oxygen saturation proves more stable and with values closer to baseline), and allows dental treatment to be performed on healthy, lacking cooperative ability children who otherwise could not be treated with local anesthesia alone. No side effects were observed in either group.

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“…The hemodynamic indexes of the two groups at different time points were detected and compared, respectively, before anesthesia, before intubation, 1min after intubation, 1min and 5min after extubation [3] . Visual analogue pain scale was used to evaluate and compare the pain degree at 6h, 12h and 24h after surgery between the two groups [4] .…”

Section: Research Indicatorsmentioning

confidence: 99%

Anesthetic Effect of Sufentanil Combined with Remifentanil in Patients Undergoing Radical Gastrectomy

Wang

2021

JCNR

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Objective: To explore and analyze the anesthetic effect of sufentanil combined with remifentanil in patients undergoing radical gastrectomy for gastric cancer. Methods: In this study, 100 patients receiving radical gastrectomy for gastric cancer in our hospital were selected as the research subjects, and the period from June 2019 to February 2021 was divided into different anesthesia regimens. Fifty patients receiving remifentanil anesthesia were used as the control group, and 50 patients receiving remifentanil combined with sufentanil anesthesia were used as the research group. The anesthetic effect of the two groups of patients was analyzed and compared. Results: The HR and MAP of the study group at different time after intubation were lower than those of the control group (P<0.05). The changes of HR and MAP before and after intubation in two groups were significant compared with those before intubation (P<0.05). The postoperative VAS score of the study group was significantly better than that of the control group (P<0.05). Conclusions: In radical gastrectomy for gastric cancer, the choice of sufentanil and remifentanil as the anesthesia scheme can effectively stabilize the hemodynamics of patients, relieve the degree of postoperative pain, with obvious clinical value.

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Anesthetic effect of propofol combined with remifentanil or sevoflurane anesthesia on patients undergoing radical gastrectomy

Cited by 5 publications

References 23 publications

Effects of intravenous anesthesia with sevoflurane combined with propofol on intraoperative hemodynamics, postoperative stress disorder and cognitive function in elderly patients undergoing laparoscopic surgery

Effects of intravenous anesthesia with sevoflurane combined with propofol on intraoperative hemodynamics, postoperative stress disorder and cognitive function in elderly patients undergoing laparoscopic surgery

Comparison of hemodynamic changes with general or local anesthesia during dental treatment in pediatric patients: A prospective clinical study

Anesthetic Effect of Sufentanil Combined with Remifentanil in Patients Undergoing Radical Gastrectomy

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