Anesthesia for Congenital Heart Disease 2005
DOI: 10.1002/9780470754986.ch4
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Anesthetic Agents and Their Cardiovascular Effects

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Cited by 3 publications
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“…Ketamine is commonly used in the management of the unstable patient, as it tends to increase cardiac output via central and peripheral sympathomimetic effects. Favorable hemodynamic responses have been reported in the setting of noncardiac surgery for children with severe heart failure (22) and prior to heart transplantation in adults (23). However, a direct myocardial depressant effect may be revealed when ketamine is administered to patients whose sympathomimetic responses are already maximally stimulated (24).…”
Section: Discussionmentioning
confidence: 99%
“…Ketamine is commonly used in the management of the unstable patient, as it tends to increase cardiac output via central and peripheral sympathomimetic effects. Favorable hemodynamic responses have been reported in the setting of noncardiac surgery for children with severe heart failure (22) and prior to heart transplantation in adults (23). However, a direct myocardial depressant effect may be revealed when ketamine is administered to patients whose sympathomimetic responses are already maximally stimulated (24).…”
Section: Discussionmentioning
confidence: 99%
“…The management of cardiac tamponade is based on supporting right ventricular preload, heart rate, and contractility (54,55). To achieve these goals, we first administered a preinduction fluid bolus as the patient had been nil per os for some time and was also thought to have had pulmonary bleeding.…”
Section: Discussionmentioning
confidence: 99%
“…Finally, we used ketamine for sedation during intravenous access. Although ketamine has desirable indirect sympathomimetic properties (56), this drug is not always appropriate for tamponade because it also possesses direct myocardial depressant activity. In the acute trauma setting this latter effect is rarely a problem, but when cardiac reserve is low and endogenous catecholamines are depleted (e.g., pericardial effusion associated with long‐term illness), ketamine’s negative inotropism may be unmasked resulting in hemodynamic instability (54).…”
Section: Discussionmentioning
confidence: 99%