Anesthesia in Pediatric Dentistry

Лазарев, В. В.; Haliullin, Dinar M.

doi:10.21292/2078-5658-2019-16-4-31-37

Cited by 2 publications

(1 citation statement)

References 28 publications

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“…Обзор литературы о применении ксенона в детской стоматологии выполнен с исполь зованием медицинских баз данных PubMed, Scopus, The Cochrane Library, CyberLeninka. Оказалось, что использование в стоматоло гической практике в качестве ингаляционного анестетика ксенона является перспективным, однако, сведения по его применению у детей ограничены [40].…”

Section: результаты и их анализunclassified

Prospects of Xenon Application in Functional Recovery and Rehabilitation of Patients Working in Extreme Occupational Environments

Ушаков

Pyatibrat

2023

Med.-biol. soc.-psihol. probl. bezop. črezvyčajnyh situac.

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Relevance. Professionals working in extreme environments (army officers, police officers, pilots, divers, firefighters, rescue workers, etc.) are susceptible to overstraining their functional reserves, causing occupational overexposure or even death. It is therefore pivotal to optimize the functional condition of individuals working in extreme occupational environment.The objective is to analyse the prospects for xenon medical application, including to promote functional optimization and occupational resilience in professionals working in extreme occupational environment.Methods. The authors studied the research papers published in the Russian Science Citation Index [https://elibrary.ru/] and PubMed [https://pubmed.ncbi.nlm.nih.gov] over the last decade.Results and Discussion. Current research analysis has revealed numerous investigations regarding xenon application in addiction medicine, treatment of post-traumatic stress disorders, and improvement of physiological reserve and occupational resilience, as well as in anesthesiology. Regrettably, our review of Russian and international publications has failed to answer the pivotal issue regarding pharmacological mechanisms behind xenon action. A few research papers hypothesized without evidence that ionotropic glutamate receptors (NMDA-receptors) might be involved in antinociceptive effects.Conclusion. Xenon is a promise and can be appropriately applied in the treatment and rehabilitation of individuals working in extreme occupational environments.

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Section: результаты и их анализunclassified

Prospects of Xenon Application in Functional Recovery and Rehabilitation of Patients Working in Extreme Occupational Environments

Ушаков

Pyatibrat

2023

Med.-biol. soc.-psihol. probl. bezop. črezvyčajnyh situac.

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Choice of Anesthesia for Orthopedic Surgery in Elderly and Senile Patients (Review)

Lisichenko

Gusarov

2022

Obŝaâ reanimatologiâ

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Management of elderly and senile patients is a major challenge due to signiﬁcant comorbidity, especially in surgery under general anesthesia.The aim of the review was to identify the optimal method of anesthesia for knee arthroplasty in elderly patients based on the available clinical and experimental studies.We searched PubMed, Medline, and Elibrary.ru databases for relevant sources. Out of more than 300 publications initially analyzed, 113 literature sources (dating from 1951 to 2021) were included in the review, of which 80 were published within the last ﬁve years (2016–2021). The inclusion criteria were high informative value and relevance, except for sources cited as historical references. Both randomized multicenter studies and individual case reports were included in the review. Exclusion criteria were low informative value, outdated and repetitive data.We reviewed the physiology of elderly and senile patients, various variants of anesthesia, the use of neuroaxial anesthesia and peripheral regional blocks, xenon-based general anesthesia, assessed the advantages and drawbacks of each method, and discussed the monitoring of the depth of anesthesia and the issues of inraoperative awareness during knee arthroplasty in elderly and senile patients.Conclusion. The choice of anesthesia for knee arthroplasty in elderly and senile patients should be based on the risks of decompensation of cardiovascular comorbidities and cognitive impairment. No known anesthetic method is ideal in terms of safety. The use of xenon as the main anesthetic seems promising due to its cardio- and neuroprotective properties. However, its use is limited due to relatively high cost. Therefore, the search for optimal (lower than recommended) inhalation concentrations may lead to expanding use of xenon in elderly and senile patients. At the same time, the use of lower concentrations of the drug is associated with the intraoperative awakening and the need for its combination with narcotic analgesics or amnestic agents, which may not be optimal. In addition, the protective eﬀect of xenon retrograde amnesia against the stress of unintended intraoperative awakening has not been studied, and routine methods of monitoring the depth of hypnosis when using xenon often yield skewed measurement results inconsistent with the clinical manifestations of anesthesia.Therefore, there is a need for further studies concerning the retrograde amnesic eﬀect of xenon and search for optimal methods of assessing the depth of hypnosis when using this gas to safely reduce its inhalation concentration.

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Anesthesia in Pediatric Dentistry

Cited by 2 publications

References 28 publications

Prospects of Xenon Application in Functional Recovery and Rehabilitation of Patients Working in Extreme Occupational Environments

Prospects of Xenon Application in Functional Recovery and Rehabilitation of Patients Working in Extreme Occupational Environments

Choice of Anesthesia for Orthopedic Surgery in Elderly and Senile Patients (Review)

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