Anesthesia in a young adult with opsoclonus-myoclonus syndrome

Lee, Jeongwoo; Kim, Deokkyu; Jeon, Byeongdo; Oh, Jiyoun; Han, Young Jin

doi:10.4097/kjae.2014.67.s.s5

Cited by 4 publications

(5 citation statements)

References 4 publications

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“…Despite being a case report, with the limitations associated with this type of scientific evidence, this article comprises one of the five published cases[ 2 3 4 5 ] about anesthesia management in OMS and is the first one to describe a successful combined neuraxial-general approach.…”

Section: Discussionmentioning

confidence: 99%

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Combined neuraxial-general anesthesia in opsoclonus–myoclonus syndrome: A case report

et al. 2023

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Opsoclonus-myoclonus syndrome (OMS) is a very rare neurological disorder thought to be the result of autoimmune responses in the nervous system. The relationship between this disorder and anesthesia procedures has not been studied in detail. To our knowledge, there are only 4 case reports, none of them with epidural-general combined anesthesia. We present a 9-year-old female with OMS due to low-grade neuroblastoma, for 7 years, who underwent tumor remotion due to the large size. Intravenous induction was done with alfentanil, lidocaine, propofol and rocuronium and ropivacaine was administered via lumbar epidural catheter. Adding to the sparse anesthetic management information in OMS, we now show one more possible approach, that can be valuable in high-risk cases, where general anesthesia can be involved with higher risk for the patient.

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Section: Discussionmentioning

confidence: 99%

“…OMS is a rare disease and its relationship with anesthesia procedures has not been studied in detail. To our knowledge, there are only four case reports describing anesthesia management of OMS,[ 2 3 4 5 ] none of them with epidural-general anesthesia.…”

mentioning

confidence: 99%

Combined neuraxial-general anesthesia in opsoclonus–myoclonus syndrome: A case report

et al. 2023

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“…Fentanyl and propofol have been reported to be safe with established OMS,7 while other anaesthetic agents as ketamine and etomidate aggravate the opsoclonus and myoclonus 8…”

Section: Discussionmentioning

confidence: 99%

Postintervention acute opsoclonus myoclonus syndrome

Aquilina¹,

Dingli

Aquilina

2017

BMJ Case Reports

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Opsoclonus myoclonus syndrome (OMS) is a rare, neurological condition affecting 1 in 10 000 000 people annually. Opsoclonus, defined as involuntary rapid, multivectorial oscillations of the eyes, together with ataxia and myoclonus are usually present. OMS may be paraneoplastic: often associated with occult neuroblastoma in childhood and with breast carcinoma or small cell lung carcinoma in adults. Other aetiologies include viral or toxic agents. The pathogenesis is thought to be immune mediated. A 37-year-old woman with previous inflammatory cranial mononeuropathies was admitted for elective dilatation and curettage (D&C). Immediately after she complained of left-sided paraesthesia and later became disoriented, with incoherent speech, inability to obey commands, opsoclonus of the eyes and myoclonic jerks. Investigations including onconeuronal antibodies, cerebrospinal fluid analysis, and imaging were normal. She was treated with intravenous methylprednisolone with rapid improvement. Previous surgeries with anaesthesia were uncomplicated. The anaesthetic agents used for the D&C were fentanyl and propofol.

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“…The effect of anesthesia on OMS has not been studied in detail due to the rarity of the disease and three case reports on anesthesia management have been reported till date. [ 8 9 10 ] Burrows and Seeman[ 8 ] successfully administered anesthesia in a child with a kidney tumor and Kinsbourne syndrome using morphine, pancuronium, and nitrous oxide. They reported worsening of myoclonus and opsoclonus when intramuscular ketamine was used in the same patient for sedation during myelogram.…”

Section: Discussionmentioning

confidence: 99%

“…Lee et al . [ 10 ] used propofol and remifentanil for total intravenous anesthesia and noticed that opsoclonus and myoclonus disappeared once the target concentration was achieved.…”

Section: Discussionmentioning

confidence: 99%

Anesthesia in a child with Kinsbourne syndrome: Does anesthesia technique matters?

2016

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Kinsbourne syndrome is a rare neurological paraneoplastic syndrome associated with neuroblastic tumors. There are very few literatures on its anesthetic management and interaction with anesthetic agents. The epileptogenic potential of certain anesthetic agents such as ketamine, etomidate, and meperidine might trigger opsoclonus and myoclonus and have an impact on the long-term neurological outcome. The objective of this case report is to discuss the safety of anesthetic agents and their relationship in a patient with Kinsbourne syndrome. We discuss our experience in the anesthetic management of a child with Kinsbourne syndrome with ganglioneuroblastoma in the thoracic paravertebral space.

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Anesthesia in a young adult with opsoclonus-myoclonus syndrome

Cited by 4 publications

References 4 publications

Combined neuraxial-general anesthesia in opsoclonus–myoclonus syndrome: A case report

Combined neuraxial-general anesthesia in opsoclonus–myoclonus syndrome: A case report

Postintervention acute opsoclonus myoclonus syndrome

Anesthesia in a child with Kinsbourne syndrome: Does anesthesia technique matters?

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