Anesthesia for the Pregnant HIV Patient

Hignett, Rachel; Fernando, Roshan

doi:10.1016/j.anclin.2007.11.002

Cited by 13 publications

(7 citation statements)

References 45 publications

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“…There are concerns regarding cardiac problems (myocarditis, cardiomyopathy, accelerated atherosclerosis) with protease inhibitors, respiratory opportunistic infections (bacterial pneumonias and aspergillosis), central nervous system involvement (encephalopathy, demyelinating syndromes, infection induced space occupying lesions, dementia among others), diarrhea along with associated electrolyte abnormalities, nephropathy (may be associated with protease inhibitors like adefovir and indinavir), pancytopenia (aggravated by nucleoside reverse transcriptase inhibitors (NRTIs), thrombotic episodes in late stages, metabolic problems (lipodystrophy, insulin resistance aggravated by protease inhibitors), lactic acidosis and pancreatitis with NRTIs, allergic reactions and hepatic involvement with non-nucleoside reverse transcriptase inhibitors (NNRTIs), apart from autonomic and peripheral neuropathy which are quite common in HIV positive patients. 15 Oropharyngeal and esophageal pathology may make some patients susceptible to difficult intubation, regurgitation and aspiration. 16 Protease inhibitors and non-nucleoside reverse transcriptase inhibitors are the most commonly implicated group of anti-retrovirals in drug interactions.…”

Section: Discussionmentioning

confidence: 99%

HIV in Women: The Gynecological Frontier

Goswami

Chattopadhyay

2014

Nepal j. obstet. gynaecol.

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Aims: The objective of the paper was to study the spectrum of gynecological disorders in HIV positive woman, which are often not given much importance as the issue of antiretroviral therapy and management of opportunistic infections occupy the major share of their treatment strategy. Methods: It was an observational study which included 135 women. The study was conducted in the Medical College and Hospital, Kolkata from January 2010 to December 2012 after obtaining permission from the institutional ethics committee. All the HIV positive women who came to the gynecological outpatient department with gynecological complaints were included in the study. Results: The seropositive women suffered from the same range of gynecological problems as in non-infected women. The most common complaints at presentation were vaginal white discharge and pruritus vulvae. The most common post-operative complication was fever. Conclusions: The HIV/AIDS is taking the shape of a generalized epidemic and with the advances in the antiretroviral therapy, the life expectancy of the patients is increasing. With the improvement of survival more and more of HIV positive women would present with problems pertaining to any system of the body and the gynecological complaint is not an exception. Addressing these problems would lead to boosting up of the care and support of this subset of women.Nepal Journal of Obstetrics and Gynaecology / Vol 8 / No. 2 / Issue 16 / July-Dec, 2013 / 21-25 DOI: http://dx.doi.org/10.3126/njog.v8i2.9761

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Section: Discussionmentioning

confidence: 99%

HIV in Women: The Gynecological Frontier

Goswami

Chattopadhyay

2014

Nepal j. obstet. gynaecol.

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“…В некоторых работах отмечены клинически значимые взаимодействия между антиретровирусными препаратами и препаратами для анестезии. Так, ингибиторы протеаз и ненук леозидные ингибиторы обратной транскриптазы взаимодейст вуют с бензодиазепинами (диазепам, мидазолам), потенцируя действие последних, что говорит о необходимости снижения дозы атарактиков при проведении анестезии [25]. У пациенток с ВИЧ инфекцией повышена чувствительность и к нейролеп тикам.…”

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“…Нуклеозидные инги биторы обратной транскриптазы способны подавляюще дейст вовать на мегакариоцитарный росток красного костного мозга и снижать выработку тромбоцитов [12]. Тромбоцитопения на фоне проводимой АРВТ диктует необходимость включения в комплекс предоперационной подготовки пульс терапию глю кокортикоидами [25,31].…”

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Antiretroviral Therapy Complications and Their Correction in HIV-Infected Pregnant Women in the Perioperative Period

Shifman¹,

Вартанов²,

Хуторская³

et al. 2011

rmt

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“…У деяких роботах відзначено клі нічно значущі взаємодії між антиретровірусними препара тами та препаратами для анестезії. Так, інгібітори протеаз і ненуклеозидні інгібітори зворотної транскриптази взаємо діють з бензодіазепінами (діазепам, мідазолам), потенцію ючи дію останніх, що свідчить про необхідність зниження дози атарактиків при проведенні анестезії [10]. У пацієнток з ВІЛінфекцією підвищена чутливість і до нейролептиків.…”

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An anesthesiologist’s view of problems in HIV-positive patients

Grigimalsky

Garga

Тарасов

et al. 2018

prmd

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Currently, HIV infection is becoming epidemic. More than 42% of HIV-infected people in the world are women of childbearing age. With the onset of antiretroviral therapy, chemoprophylaxis during pregnancy, and planned cesarean section, the risk of perinatal HIV transmission decreases to 1–2%. However, various side effects such as anemia, neutropenia, thrombocytopenia, fatty liver dystrophy, toxic hepatitis, acute pancreatitis, increased serum transaminases, changes in biochemical parameters of liver function, impaired glucose tolerance, and hypocoagulation may occur in the context of antiretroviral therapy. This poses to the anesthesiologist a number of new tasks to ensure patient safety during the perioperative period.

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Anesthesia for the Pregnant HIV Patient

Cited by 13 publications

References 45 publications

HIV in Women: The Gynecological Frontier

HIV in Women: The Gynecological Frontier

Antiretroviral Therapy Complications and Their Correction in HIV-Infected Pregnant Women in the Perioperative Period

An anesthesiologist’s view of problems in HIV-positive patients

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