Anesthesia for patients with psychiatric illnesses: a narrative review with emphasis on preoperative assessment and postoperative recovery and pain

Stamenković, Dušica; Selvaraj, Sudhakar; Venkatraman, Shalaka; Arshad, Aleena; Rančić, Nemanja; Dragojević-Simić, Viktorija; Miljković, Milijana; Cattano, Davide

doi:10.23736/s0375-9393.20.14259-7

Cited by 5 publications

(3 citation statements)

References 93 publications

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“…There is no difference in the incidence of adverse reactions between the use of this low‐dose esketamine and the use of sufentanil 49 . Some scholars believe that when anaesthetizing patients with severe depression, it may be beneficial to give preference to esketamine, but it lacks clinical evidence and needs to be confirmed 50 . For some specific operations, such as breast disease surgery and laparoscopic hysterectomy, it will bring great psychological pressure to patients.…”

Section: Clinical Application Of Esketaminementioning

confidence: 99%

“…49 Some scholars believe that when anaesthetizing patients with severe depression, it may be beneficial to give preference to esketamine, but it lacks clinical evidence and needs to be confirmed. 50 For some specific operations, such as breast disease surgery and laparoscopic hysterectomy, it will bring great psychological pressure to patients. S‐ketamine administered after induction of anesthesia can improve the mood of patients in the short term after surgery, and has an analgesic effect.…”

Section: Clinical Application Of Esketaminementioning

confidence: 99%

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Research advances in the clinical application of esketamine

Zhang

Liu

et al. 2022

Ibrain

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Esketamine is dextrorotatory ketamine, which is an enantiomer of ketamine. Compared with ketamine, it has the advantages of a fast metabolism, fewer side effects, and strong pharmacological effects, so it is more suitable for clinical use. Esketamine has a powerful analgesic effect and has little effect on breathing. It has a wide range of applications in the fields of pediatric anesthesia, conscious sedation anesthesia, and emergency analgesia. In addition, it is also used for pain that is difficult to relieve with conventional drugs and to prevent postoperative pain. Various routes of administration are also suitable for patients who need short‐term analgesia and sedation. As a drug, esketamine inevitably brings some side effects when it is used clinically. In this article, by introducing the mechanism of action and pharmacological characteristics of esketamine, its clinical application is reviewed, and it provides a reference for the more reasonable and safe clinical application of esketamine.

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Section: Clinical Application Of Esketaminementioning

confidence: 99%

Section: Clinical Application Of Esketaminementioning

confidence: 99%

Research advances in the clinical application of esketamine

Zhang

Liu

et al. 2022

Ibrain

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“…and has lower incidence of mental side effects during recovery [9]. Compared with opioids, esketamine has both analgesic effect and almost no inhibition on breathing and circulation [10]. Studies have con rmed that the esketamine as the sole intraoperative analgesic in cardiac surgery barely alters the patient's hemodynamics [11].…”

Section: Introductionmentioning

confidence: 99%

Effect of perioperative continuous infusion of S-ketamine on the quality of postoperative recovery of patients undergoing modified radical mastectomy: a randomized controlled trial

Zhang

Yuan

Wang

et al. 2022

Preprint

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Background: Patients undergoing modified radical mastectomy (MRM) often suffer some postoperative adverse events such as acute pain, mental abnormalities, and sleep disorders. This study aim to explore the effect of esketamine as the sole intraoperative analgesic on the quality of postoperative recovery in patients undergoing MRM.Methods: Ninety-eight female patients scheduled for elective MRM were randomly divided into two groups: the esketamine group (group E) or remifentanil group (group R). In group E, anesthesia was induced with etomidate, midazolam, esketamine, and rocuronium, and maintained with intravenous propofol and esketamine. In group R, anesthesia was induced with etomidate, midazolam, rocuronium, and remifentanil, and maintained with propofol and remifentanil. The scores of the Quality of Recovery (QoR-40) questionnaire, and Pittsburgh Sleep Quality Index (PSQI) were evaluated at 1 d, 3 d, 7 d, and 30 d after surgery as primary outcome and main secondary outcome respectively. Other secondary outcomes including intraoperative hemodynamics, postoperative inflammatory indicator, and the incidence of adverse events (e.g., vomiting and dizziness) during hospitalization were also recorded.Main Results: QoR-40 total scores in group E were higher than group R at 1 d [160.71±9.811 VS 146.94±7.375, P＜0.001], 3 d [168.45±9.670 VS 152.90±8.089, P＜0.001], 7 d [180.06±7.367 VS 175.20±6.334, P=0.001] postoperatively. The PSQI scores in group E were lower than group R at 1 d [14.18±1.740 VS 17.20±1.87, P＜0.001], 3 d [11.82±1.799 VS 16.31±2.133, P＜0.001], 7 d [7.71±1.814 VS 9.65±1.832, P＜0.001] after surgery. Conclusion: Our research shows that esketamine has a certain effect on improving the quality of short-term recovery after MRM.Clinical Trials Registration: Clinical Trials gov: ChiCTR2200056576. registered February 8th, 2022, http://www.chictr.org.cn/index.aspx.

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Allgemeine Aspekte in präoperativen – intraoperativen – postoperativen Abschnitten

Kapfhammer

2023

Depression, Angst Und Traumatischer Stress in Der Chirurgie

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Anesthesia for patients with psychiatric illnesses: a narrative review with emphasis on preoperative assessment and postoperative recovery and pain

Cited by 5 publications

References 93 publications

Research advances in the clinical application of esketamine

Research advances in the clinical application of esketamine

Effect of perioperative continuous infusion of S-ketamine on the quality of postoperative recovery of patients undergoing modified radical mastectomy: a randomized controlled trial

Allgemeine Aspekte in präoperativen – intraoperativen – postoperativen Abschnitten

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