Anesthesia for cesarean section in a patient with spinal muscular atrophy

Anesthesia and perioperative medical management of children with spinal muscular atrophy

“…However, there is no standard approach to general anesthetic or procedural sedation for children with SMA. Crean and Hicks (4) provide general background and approach to children with SMA and other neuromuscular disorders, but the evidence base is limited and inconclusive (5)(6)(7) or reflects case reports of adults with less severe disease (8)(9)(10). The purpose of this study is to describe children with SMA receiving anesthetic care at a pediatric hospital, their utilization of perioperative resources and to identify opportunities to improve care.…”

Dexmedetomidine for awake fiberoptic intubation in a parturient with spinal muscular atrophy type III for cesarean delivery

“…Multiple case reports describe anesthesia and analgesia for parturients with spinal muscular atrophy. [3][4][5][6][7] Dexmedetomidine, a central acting selective a 2 agonist with minimal respiratory effects, is increasingly being used to facilitate awake fiberoptic intubation. Although the effect of increasing plasma concentrations of dexmedetomidine in adult humans has been described, 8,9 at the time this case occurred the use of dexmedetomidine in a parturient had not been reported.…”

Spinal Muscular Atrophy Type II: Anesthetic Challenges and Perioperative Management

“…Adult cases are successfully managed with spinal, epidural, and general anesthesia with total intravenous anesthesia. 1 2 3 4 Some studies have successfully used rocuronium in these patients, reversing the effect with sugammadex. 5 Our patient was a young child and was posted for prolonged and difficult surgery and hence needed to be asleep.…”