Anesthesia and outcome after partial hepatectomy for adult-to-adult donor transplantation

Abstract

Live liver donation is a valuable option for organ donation that can be conducted safely with a multidisciplinary perioperative approach. Future considerations should focus on the recovery period and how the intraoperative management can be optimized to minimize the impact of surgery on donors' quality of life.

Effect of stroke volume variation‐directed fluid management on blood loss during living‐donor right hepatectomy: a randomised controlled study

“…Living-donor liver transplantation is increasingly being used as an effective treatment for patients with endstage liver disease [1]. Any strategy to reduce blood loss during hepatectomy is important and various surgical [2,3] and anaesthetic [4][5][6] methods have been reported.…”

Comparison of Thoracic Epidural vs Paravertebral Patient Controlled Analgesia After Donor Hepatectomy

“…Hwang ve ark. (5) , tarafından ameliyat sonrası donörlerin en az 3 ay hem fiziksel hem de psikolojik yönden olumsuz etkilendikleri ve bunun yaşam kalitelerini olumsuz etkileyebildiği bildirilmiştir. Bundan dolayı karaciğer vericilerinde postoperatif ağrının etkili ve güvenli bir şekilde yönetilmesi gerekmektedir.…”

Anesthesia in Liver Transplantation

“…Despite the absence of definitive data about adverse outcome, since hydroxyethyl starch solutions are known to effect the coagulation system, they should be used with caution. 5% albumin can be used after hepatectomy, but it has also no proven benefit (Hwang and McCluskey, 2010).…”

“…Hwang and McCluskey reported that intravenous patient-controlled analgesia or intrathecal morphine may become an alternative for pain control in living donors. Regional techniques such as paraspinal blocks, transversus abdominus plane blocks, incisional field blocks are still investigated for their effect and safety in these patients (Hwang and McCluskey, 2010).…”

“…Appropriate antibiotic prophylaxis (at least 20 minutes before skin incision) including a third-generation cephalosporin and metronidazol covering anaerobic infections, in addition to venous thromboembolism prophylaxis including subcutaneous heparin or low-molecular weight heparin with pneumatic compression stockings should be administered. Prior to donor graft perfusion 1000-5000 IU intravenous heparin is administered and its reversal is often not needed (Hwang and McCluskey, 2010).…”