Anenzephalie im 20-Schwangerschaftswochen-Screening - Wann ist der richtige Zeitpunkt für die frühe Diagnose?

Abstract

Anencephaly is a lethal defect resulting from a disturbed closure of the neural tube. Prenatal diagnosis during first-trimester-scan is essential but implies pitfalls. Three findings of anencephaly at 20 weeks gestation are reported. Fetuses with anencephaly are correctly identified at 12 to 13 weeks gestation. Anencephaly occurs in absence of the cranial vault. Ultrasound findings can be normal until onset of ossification has definitely failed. A first trimester scan at 12 to 13 weeks allows reliable diagnosis and active management of anencephaly. At this gestational age fetal anatomy can be screened in detail by transvaginal ultrasound and nuchal translucency can be measured.

Clinical Profile of Congenital Structural Defects in Pregnant Women Seeking for Medical Termination of Pregnancy in Second Trimester of Pregnancy at A Teaching Hospital. (2023)

“…At 12 to 13 weeks, a first trimester scan allows for accurate diagnosis and aggressive care of anencephaly. 12 Among CVS Anomalies hypoplastic left heart syndrome was seen in 4 cases which is one of the serious conditions and life-threatening substantial anomaly where one of the options offered to the couple is MTP as suggested evidence study done by Claxon-McKinney B. 13 Besides that, 7.63% cases were diagnosed with musculoskeletal abnormalities among musculoskeletal structural abnormalities 6(4.58%) cases were of skeletal dysplasia.…”