Anemia in Inflammatory Bowel Disease: The Opening of Pandora’s Box?

Fiorino, Gionata; Allocca, Mariangela; Danese, Silvio

doi:10.1016/j.cgh.2015.06.004

Cited by 5 publications

(3 citation statements)

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“…Anemia is considered the most frequent extraintestinal manifestation of inflammatory bowel disease (IBD), usually complicating the course both in ulcerative colitis (UC) and Crohn disease (CD). 1 , 2 It is detected in up to 20% of outpatients and 70% of hospitalized patients with IBD. 3 – 5 In the majority of cases, IBD-associated anemia represents a combination of chronic iron deficiency and anemia of chronic disease.…”

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confidence: 99%

Intravenous Versus Oral Iron for the Treatment of Anemia in Inflammatory Bowel Disease

et al. 2016

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Section: Introductionmentioning

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Intravenous Versus Oral Iron for the Treatment of Anemia in Inflammatory Bowel Disease

et al. 2016

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“…Figura 2. Tratamiento por objetivos en la anemia por deficiencia de hierro en pacientes con enfermedad inflamatoria intestinal 63…”

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Anemia en la enfermedad inflamatoria intestinal: un objetivo subestimado

2022

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Anemia is the most common extraintestinal manifestation of inflammatory bowel disease (IBD). Although there are several causes of anemia in IBD, the two most frequent etiologies are iron deficiency anemia and anemia of chronic disease. Despite the high prevalence of anemia in IBD and its significant impact on patient´s quality of life, this complication is still underdiagnosed and undertreated by providers. Active screening for anemia, structured assessment, comprehensive management, and multidisciplinary collaboration are needed in IBD patients. The cornerstone of anemia management depends on the underlying etiology along with normalization of inflammatory activity. Although, oral iron is effective for the treatment of mild iron deficiency-related anemia, intravenous iron formulations have a good safety profile and can be used as first-line therapy in patients with active IBD, severe anemia and previous intolerance prior to oral iron. After proper treatment of anemia, careful monitoring is necessary to prevent its recurrence. Herein, we discuss the etiology, screening, diagnosis, therapy selection, and follow-up for anemia in IBD.

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“…Additional measures that could yield better postoperative outcomes include intravenous iron supplementation or blood transfusions to correct anemia, which is present in the majority of older patients, before surgery. 27,28 Minimizing or decreasing steroid exposure also could reduce lower postoperative morbidity. 29,30 In the postoperative setting, having routine protocols in place to monitor for surgical site infections (particularly postdischarge), prompt removal of indwelling catheters, physical and occupational therapy services, and routine use of incentive spirometry and thromboembolism prophylaxis is essential to help offset increased risks associated with chronologic age.…”

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confidence: 99%

To Operate or Not to Operate in Inflammatory Bowel Disease: Is Older Age the Only Question?

2016

Clinical Gastroenterology and Hepatology

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Anemia in Inflammatory Bowel Disease: The Opening of Pandora’s Box?

Cited by 5 publications

References 16 publications

Intravenous Versus Oral Iron for the Treatment of Anemia in Inflammatory Bowel Disease

Intravenous Versus Oral Iron for the Treatment of Anemia in Inflammatory Bowel Disease

Anemia en la enfermedad inflamatoria intestinal: un objetivo subestimado

To Operate or Not to Operate in Inflammatory Bowel Disease: Is Older Age the Only Question?

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