Anemia and Oxygen Delivery

Bliss, Stuart P.

doi:10.1016/j.cvsm.2015.04.006

Cited by 8 publications

(2 citation statements)

References 58 publications

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“…Pain, acute blood loss, inflammation and the hypermetabolic stress phase make the recovery period a state of grave physiologic insult. 7,12,22,23 Coupled with the body's blunted physiologic compensatory response caused by anesthesia and the use of analgesics, the recovering anemic surgical patient is uniquely vulnerable. 24 Moreover, chronic iron deficiency is associated with physiologic dysregulation in acute stress.…”

Section: Discussionmentioning

confidence: 99%

“…1,6 Iron deficiency not only causes anemia but can also have a detrimental effect on tissue healing and the body's adaptation to stress. 7,8 Several publications have investigated preoperative interventions to treat iron deficiency anemia, including oral and intravenous iron administration, which have been shown to increase patients' hemoglobin level above anemia thresholds. [9][10][11] Preoperative anemia is known to be an independent risk factor for morbidity and composite mortality in high-risk surgical patients across multiple specialties.…”

Section: Introductionmentioning

confidence: 99%

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The effect of anemia severity on postoperative morbidity among patients undergoing laparoscopic hysterectomy for benign indications

Tyan

Taher

Carey

et al. 2019

Acta Obstet Gynecol Scand

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Introduction: One-third of non-pregnant women worldwide are anemic. 1 Anemia is a known independent risk factor for postoperative morbidity. 2 Given that the vast majority of hysterectomies are not performed in the emergency setting, we designed this study to evaluate the effect of preoperative anemia on postoperative morbid-How to cite this article: Tyan P, Taher A, Carey E, et al. The effect of anemia severity on postoperative morbidity among patients undergoing laparoscopic hysterectomy for benign indications.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

The effect of anemia severity on postoperative morbidity among patients undergoing laparoscopic hysterectomy for benign indications

Tyan

Taher

Carey

et al. 2019

Acta Obstet Gynecol Scand

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Anemia

DiFazio¹,

Hackner

2018

Textbook of Small Animal Emergency Medicine

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Reduced deep regional cerebral venous oxygen saturation in hemodialysis patients using quantitative susceptibility mapping

Chai

Liu²,

Liu

et al. 2017

Metab Brain Dis

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Cerebral venous oxygen saturation (SvO) is an important indicator of brain function. There was debate about lower cerebral oxygen metabolism in hemodialysis patients and there were no reports about the changes of deep regional cerebral SvO in hemodialysis patients. In this study, we aim to explore the deep regional cerebral SvO from straight sinus using quantitative susceptibility mapping (QSM) and the correlation with clinical risk factors and neuropsychiatric testing 52 hemodialysis patients and 54 age-and gender-matched healthy controls were enrolled. QSM reconstructed from original phase data of 3.0 T susceptibility-weighted imaging was used to measure the susceptibility of straight sinus. The susceptibility was used to calculate the deep regional cerebral SvO and compare with healthy individuals. Correlation analysis was performed to investigate the correlation between deep regional cerebral SvO, clinical risk factors and neuropsychiatric testing. The deep regional cerebral SvO of hemodialysis patients (72.5 ± 3.7%) was significantly lower than healthy controls (76.0 ± 2.1%) (P < 0.001). There was no significant difference in the measured volume of interests of straight sinus between hemodialysis patients (250.92 ± 46.65) and healthy controls (249.68 ± 49.68) (P = 0.859). There were no significant correlations between the measured susceptibility and volume of interests in hemodialysis patients (P = 0.204) and healthy controls (P = 0.562), respectively. Hematocrit (r = 0.480, P < 0.001, FDR corrected), hemoglobin (r = 0.440, P < 0.001, FDR corrected), red blood cell (r = 0.446, P = 0.003, FDR corrected), dialysis duration (r = 0.505, P = 0.002, FDR corrected) and parathyroid hormone (r = -0.451, P = 0.007, FDR corrected) were risk factors for decreased deep regional cerebral SvO in patients. The Mini-Mental State Examination (MMSE) scores of hemodialysis patients were significantly lower than healthy controls (P < 0.001). However, the deep regional cerebral SvO did not correlate with MMSE scores (P = 0.630). In summary, the decreased deep regional cerebral SvO occurred in hemodialysis patients and dialysis duration, parathyroid hormone, hematocrit, hemoglobin and red blood cell may be clinical risk factors.

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Anemia and Oxygen Delivery

Cited by 8 publications

References 58 publications

The effect of anemia severity on postoperative morbidity among patients undergoing laparoscopic hysterectomy for benign indications

The effect of anemia severity on postoperative morbidity among patients undergoing laparoscopic hysterectomy for benign indications

Anemia

Reduced deep regional cerebral venous oxygen saturation in hemodialysis patients using quantitative susceptibility mapping

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