Androgenetic alopecia: Clinical features and trichoscopy

Bansod, Shashank; Sharma, Aseem; Mhatre, Madhulika

doi:10.4103/cdr.cdr_1_22

Cited by 3 publications

(1 citation statement)

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“…[1] Bansod et al demonstrated that 30% of AGA cases in men occur after the age of 30, which can increase to 50% by the age of 50. [4] Halilovic-Kasumagic et al identi ed trichoscopic features of AGA including hair diameter diversity > 20% (100%), yellow dots (52.88%), vellus hair (49.03%), and perifollicular hyperpigmentation (40.38%). [2] Despite being a non-life-threatening condition, a common concern of AGA is cosmetic disturbance and decreased self-con dence in patients due to their appearance.…”

Section: Introductionmentioning

confidence: 99%

The Comparison of Metabolic Syndrome Parameters, Trichoscopic and Trichoscan Characteristics in Androgenetic Alopecia (AGA) and Early-Onset Androgenetic Alopecia (Early-Onset AGA)

Legiawati,

Sitohang,

Yusharyahya

et al. 2024

Preprint

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Androgenetic alopecia (AGA), the most common cause of hair loss, is influenced by various risk factors. Metabolic syndrome constitutes a collection of risk factors elevating the risk of cardiovascular disease. The presence of early-onset AGA could serve as an indicator of the emergence of metabolic syndrome, yet to date, no research has examined these parameters in AGA. This is a cross-sectional study comparing two groups; early onset versus normal onset AGA. Forty participants were enlisted and evenly distributed into the two groups. Subsequently, participants underwent examinations utilizing trichoscopy, trichoscan, and laboratory assessments. Apart from waist circumference, BMI, and age of alopecia onset, there were no notable differences concerning sociodemographic and clinical features. In terms of hair growth parameters, the telogen hair rate stands out as the sole indicator exhibiting a significant difference between both groups, while trichoscopy data also revealed varying hair characteristics. Lastly, metabolic parameters namely triglyceride, fasting blood glucose, HbA1c and HDL differ significantly, with the normal onset group demonstrating a higher prevalence of metabolic abnormality. This suggests a potential association between AGA and metabolic syndrome. However, the exact nature of this relationship remains uncertain, necessitating further research with larger samples, specific age groups and diverse study designs.

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Section: Introductionmentioning

confidence: 99%

The Comparison of Metabolic Syndrome Parameters, Trichoscopic and Trichoscan Characteristics in Androgenetic Alopecia (AGA) and Early-Onset Androgenetic Alopecia (Early-Onset AGA)

Legiawati,

Sitohang,

Yusharyahya

et al. 2024

Preprint

View full text Add to dashboard Cite

show abstract

The comparison of metabolic syndrome parameters, trichoscopic and trichoscan characteristics in androgenetic alopecia (AGA) and early-onset androgenetic alopecia (early-onset AGA)

Legiawati,

Sitohang,

Yusharyahya

et al. 2024

Arch Dermatol Res

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Hair Regeneration in Androgenetic Alopecia using Secretome of Adipose-derived Stem Cells (ADSC) and Minoxidil: A Comparative Study of Three Groups

Legiawati,

Sitohang,

Yusharyahya

et al. 2024

Preprint

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Introduction: Androgenetic alopecia (AGA) is one of the most common cause of hair loss disorder, characterized by the shortening duration of anagen phase, increased telogen phase, and miniaturization of hair follicles, eventually leading to their regression. This disorder tends to progress into partial or even complete baldness. Several therapeutic options are now available for AGA, including conventional medications such as finasteride, dutasteride, and minoxidil. However, side effects of these medications are also commonly reported. The use of adipose derived stem cells (ADSCs) and their secreted bioactive molecules, “secretome” has gained attention which could produce many effects for hair growth promotion and has been proven in clinical trials. However, there is still insufficient evidence regarding the comparison of effectiveness of secretome with treatments like minoxidil. Objective: This study aims to compare the effectiveness and safety of secretome from ADSCs with minoxidil in AGA cases, to provide future reference in the application of cell-based therapy in AGA cases. Method: 60 subjects were divided into three treatment groups (minoxidil only, secretome only, and combination of both) and were given intervention on week 0, 4, and 8. All subjects were evaluated by physical examination, photography, trichoscopy, and trichoscan until week 12. Results: All groups showed a statistically significant improvement (p <0.05) on hair growth parameters from week 4, with the best improvement observed on week 12. There were a significant difference between groups on some of the delta hair growth parameters (p <0.05), observed between secretome and combination groups. The combination group had the best improvement substantially on hair growth parameters. Side effects are minimum and only reported by the subjects in minoxidil group. Conclusion: All of the interventions give a significant improvement on hair growth with the best improvement observed after 12 weeks. However, the best improvement substantially were observed in combination group.

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Androgenetic alopecia: Clinical features and trichoscopy

Cited by 3 publications

References 0 publications

The Comparison of Metabolic Syndrome Parameters, Trichoscopic and Trichoscan Characteristics in Androgenetic Alopecia (AGA) and Early-Onset Androgenetic Alopecia (Early-Onset AGA)

The Comparison of Metabolic Syndrome Parameters, Trichoscopic and Trichoscan Characteristics in Androgenetic Alopecia (AGA) and Early-Onset Androgenetic Alopecia (Early-Onset AGA)

The comparison of metabolic syndrome parameters, trichoscopic and trichoscan characteristics in androgenetic alopecia (AGA) and early-onset androgenetic alopecia (early-onset AGA)

Hair Regeneration in Androgenetic Alopecia using Secretome of Adipose-derived Stem Cells (ADSC) and Minoxidil: A Comparative Study of Three Groups

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