“…Indeed, fibroblasts have been a favored cell in culture for assessing androgen effects. For example, AR‐expressing fibroblasts have been identified in the lung (Torday, 1984; Nielsen, 1985, 1992), dermis (Sultan et al, 1982; Kaufman and Pinsky, 1983; Kaufman et al, 1983; Dammann et al, 2000; Hellwinkel et al, 2000; Asada et al, 2001) and in the testes (Verhoeven, 1980), where they have roles in tissue morphogenesis, loss and/or growth of hair, and disease states. Fibroblasts express numerous extracellular matrix (ECM) molecules, such as collagen, laminin, and fibronectin, which, in addition to providing mechanical support to cells, also function in a variety of ways as signaling and/or cell adhesion molecules (Sanes, 1989; Alberts et al, 1994).…”