Andre G. Ombredane and the psychiatry of multiple sclerosis: A conceptual and statistical history

Berríos, Germán E.; Quemada, José Ignacio

doi:10.1016/0010-440x(90)90029-r

Cited by 6 publications

(2 citation statements)

References 15 publications

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“…Berrios and Quemada [57] highlighted the limits and merits of Ombredane's work on the basis of current diagnostic criteria and with the aid of a statistical approach. On one hand, the limits include the questionable location of some symptoms (fatigue among cognitive disorders and fatalism among affective ones) and the inconsistency of the conclusions with the data as such.…”

Section: From Charcot To the 1980s The Alternation Of Points Of Viewmentioning

confidence: 99%

Focus or Neglect on Cognitive Impairment Following the History of Multiple Sclerosis

Nocentini

2023

NeuroSci

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Cognitive disorders are now considered an integral part of the picture of multiple sclerosis. If we trace the history of the accounts of this disease, from the early descriptions by Jean-Martin Charcot, the first to provide systematic characteristics of multiple sclerosis, to present-day accounts, reports of cognitive disturbances have demonstrated an alternating trend. Cognitive disturbances were identified in the beginning, quite clearly for the times. Then, for a long time, they were considered infrequent or attributed to other factors. Finally, since the 1980s, cognitive disturbances have been the subject of increasingly in-depth studies, and are currently assumed to be a very important consequence of multiple sclerosis. In this work, the history of the description of cognitive disorders of multiple sclerosis will be retraced by analyzing the possible reasons for the differences in attention they have received over time. It emerged from the analysis that, as in the case of other pathologies, various factors have influenced how cognitive disorders have been taken into consideration. Some of these factors are inherent to the very nature of the cognitive impairments present in multiple sclerosis; others are linked to historical periods, or to the different ways of approaching the analysis of the phenomena caused by a disease. The reflections made on these topics should, among other things, increase our awareness of how scientific investigation is invariably placed in the historical context in which it is carried out.

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Section: From Charcot To the 1980s The Alternation Of Points Of Viewmentioning

confidence: 99%

Focus or Neglect on Cognitive Impairment Following the History of Multiple Sclerosis

Nocentini

2023

NeuroSci

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“…In 1929, Ombredane 6 reported a striking "fatigability" upon extensive psychiatric evaluation of 60 patients with MS, writing "the main loss was represented by difficulty in initiating mental effort toward the solution of problems and in the fatigability of mental functions." When scientific discoveries of the early 20th century enabled the identification of myelin damage and inflammation of the central nervous system (CNS) in patients with MS, major clinical meetings and publications emerged, all demonstrating concerted effort to problematize the common set of debilitating symptoms seen in patients; 7,8 at this time, the inexplicable transitory daily tiredness remained unnamed. Within the mid-20th century, however, "fatigue" emerged as the clinical term used to describe the tiredness/lassitude described by and observed in MS patients.…”

Section: Historical Overview Of Observation and Designationmentioning

confidence: 99%

What’s in a name? That which we call Multiple Sclerosis Fatigue

2020

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Very limited progress has been made to date in the treatment of debilitating Multiple Sclerosis (MS) daily onset symptoms. These daily symptoms include motor, sensory, and cognitive impairments as well as an overwhelming feeling of tiredness, often referred to as “MS fatigue.” Although widely cited as a main cause of inability to work and poor quality of life in patients with MS, daily onset MS-related tiredness continues to defy definition, and, consequently, measurement and treatment. Beginning with a historical overview of observations of daily onset MS-related tiredness, this Topical Review demonstrates how the misnomer “MS fatigue” has introduced ongoing misunderstanding for patients, investigators, clinicians, and therapists. Finally, combining current findings in clinical neuroscience with the striking set of long-standing commonalities present throughout the past 200 years of clinical observations, we underscore the immediate necessity for conceptual and applied change, to be initiated by the renaming of this distinct syndrome.

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A Happy State of Mind

Finger

1998

Arch Neurol

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Although multiple sclerosis (MS) is often looked on as a disorder of the sensory and motor systems, it can also be associated with changes in emotion and personality. Many patients with MS seem cheerful, optimistic about the future, and strangely unconcerned about their ongoing physical deterioration. In addition, patients with MS have a tendency to break into uncontrollable laughing, even when they have no reason to be happy. This article looks at how these seemingly upbeat affective changes were viewed by early researchers of MS, including Cruveilhier, Charcot, and Moxon during the 19th century and Cottrell, Wilson, and Ombredane in the 1920s. Frequently cited studies on the emotional correlates of MS from the mid-20th century are also presented, and some trends in the more recent literature are identified.

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Andre G. Ombredane and the psychiatry of multiple sclerosis: A conceptual and statistical history

Cited by 6 publications

References 15 publications

Focus or Neglect on Cognitive Impairment Following the History of Multiple Sclerosis

Focus or Neglect on Cognitive Impairment Following the History of Multiple Sclerosis

What’s in a name? That which we call Multiple Sclerosis Fatigue

A Happy State of Mind

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