Ancient Schwannoma of the True Vocal Cord

Abstract

Ancient schwannomas are benign nerve origin neoplasms that may cause difficulties in the differential diagnosis with other benign or malignant tumors. They usually occur in the head and neck region (epiglottis, arytenoepiglottic fold, false vocal cord). Involvement of the true vocal cords is extremely rare (less than 10 cases have ever been reported in the English literature – mainly in women). The present case describes a 27-year-old man who presented with a 2-year history of hoarseness. Indirect laryngoscopy showed a small polypoid mass in the middle of the left vocal cord. During microlaryngoscopy under general anesthesia, the polypoidal mass was removed and sent for histology. Immunohistochemistry and detailed histological examination revealed an ancient schwannoma. The present case in a male patient aims to increase awareness of the possibility that these tumors may also exist in the true vocal cords mimicking other more frequent lesions.

A Huge Ancient Schwannoma of the Epiglottis

“…5 Ancient schwannoma can be distinguished from other schwannomas by degenerative changes, including hemorrhage, cyst formation, calcification, perivascular hyalinization, and xanthomatous infiltration. 5 In this patient, histopathologic examination showed hemorrhage and stromal hyalinization. Therefore, the final diagnosis was ancient schwannoma of the epiglottis.…”

Laryngeal schwannoma: excision via a laryngofissure approach

“…Schwannomas are classified as having three main characteristics in order to confirm diagnosis [ 1 , 7 ]. (i) They arise in nerve sheaths and are encapsulated by a fibrous capsule consisting of epineurium and residual nerve fibres.…”

“…Schwannomas are one of the main subtypes of peripheral nerve neurogenic tumours [ 1 , 2 ]. Schwannomas were first described by Verocay in 1908 and consists of Schwann cells [ 3 ].…”

Schwannoma of Tonsillolingual Sulcus: First Case Report and Review of Literature

“…Usually, the lesion is a large sharply demarcated mass, round or oval, isoattenuated with muscle, sometimes cystic and often heterogeneously enhancing. 11 The definitive diagnosis remains histologic.…”