Anchoring of parasitic plasmids to inactive regions of eukaryotic chromosomes through nucleosome signal
Fabien Girard,
Antoine Even,
Agnès Thierry
et al.
Abstract:Natural plasmids are common in prokaryotes but few have been documented in eukaryotes. The natural 2µ plasmid present in budding yeastSaccharomyces cerevisiaeis one of the most well characterized. This highly stable genetic element coexists with its host for millions of years, efficiently segregating at each cell division through a mechanism that remains poorly understood. Using proximity ligation (Hi-C, Micro-C) to map the contacts between the 2µ and yeast chromosomes under dozens of different biological cond… Show more
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