Ancestry characterization of Ecuador’s Highland mestizo population using autosomal AIM-INDELs

Abstract

Ancestry Informative Insertion-Deletion markers have been used as a tool to infer the origin of population. In the present study, we report the results obtained for 46 AIM-INDELS in the Ecuadoŕs highland population by analyzing 171 unrelated individuals. Native American was the most prevalent ancestry in the studied population (63.1%), followed by European (30.3%) and lastly African (6.6%). The admixture found is in agreement with the historical background of Ecuador.

Ring chromosome 15 – cytogenetics and mapping arrays: a case report and review of the literature

“…Our patient came from Coca city in the Amazon region of Ecuador; according to the ancestry profile of the Ecuadorian population [ 12 ] she is a Mestizo: 63.1% Native American, 30.3% European, and 6.6% African ancestry. The first contact with our patient was in April 2016 at 11-months old, she was the second child of non-consanguineous healthy parents.…”

Characterization Of Ancestral Origin Of Cystic Fibrosis Of Patients With New Reported Mutations In CFTR

“…In Ecuador, there are studies about the ancestral origin, for instance, the Ecuadorian was reported to be composed of 59.6% of Native American, 28.8% of European and lastly 11.6% of African origin (14) (15).…”

“…Moreover, Ecuadorian self-identified as: "mestizos" 71.9%, "montubios" 7.4%, Afro-Ecuadorian 7.2%, "indígenas" 7%, "blancos" 6.1% and others (0.4%) (13). There are also reports of the Ecuadorian ancestry using AIMs in mestizo population where Native American was the most prevalent ancestry (59.6%), followed by European (28.8%) and lastly African (11.6%) (14) (15).…”

El caminar de los genes y el reloj molecular: Realidad del Ecuador

“…La encuesta evidenció el resultado de la "colonización" europea: el mestizaje (INEC 2010). Los ecuatorianos somos mestizos y la genética lo confirma (Zambrano et al 2017).…”

“…Al analizar la ancestría en más de dos mil individuos mestizos, indígenas y afros, los resultados demostraron que en promedio, los mestizos están compuestos por 61% (+23) de genes indígenas, 32% caucásicos (+13), y 7% (+3) afroecuatorianos. Analizando la ancestría, específicamente, de la sierra del Ecuador mostró datos de 63,1% de nativos americanos, 30,3% de europeos y 6,6% de africanos (Paz-Y-Miño 2014; Zambrano et al 2017). Para el ADN mitocondrial se determinó que pertenecemos a la variante ancestral amerindia A y B (Paz-Y-Miño 2014; Baeta et al 2012;Paz-Y-Miño et al 2016).…”