ANCA-associated Vasculitis: A Prothrombotic State Even in Remission?

Coagulation and Fibrinolysis Index Profile in Patients with ANCA-Associated Vasculitis

“…Therefore, a more accurate index is needed for evaluating the blood coagulation status in AAV patients. For example, Hilhorst et al used the endogenous thrombin potential (ETP), a sensitive indicator of overall plasma coagulability, to demonstrate hypercoagulability in AAV patients [17], [18]. However, since the current study was a retrospective one, such parameter was not routinely measured.…”

An unusual neurological manifestation of granulomatosis with polyangiitis: A case report and literature review

“…Being relatively young and only having one risk factor, something else had to have increased his predisposition to having an ischemic event. Review of the literature suggests that there is an association between ANCA‐associated vasculitis (AAV) and venous thromboembolic events (VTE), about 7 per 100 person‐years compared with 0.15‐0.31 in the general population . Hilhorst M, et al investigated hypercoagulability in patients with ANCA‐associated vasculitis who were in remission using the endogenous thrombin potential (ETP), an indicator of the degree of hypercoagulability.…”

Estudo da cintilografia de inalação e perfusão pulmonar em granulomatose com poliangeíte em remissão

“…Com o tratamento, as lesões parenquimatosas podem evoluir com sequelas pulmonares, porém pouco se sabe sobre alterações vasculares em sua fase de remissão. 37,52 Até o momento, existem vários trabalhos publicados na literatura médica sobre a maior incidência de eventos de tromboembolismo pulmonar e trombose venosa profunda em pacientes com granulomatose com poliangeíte 39,[53][54][55][56][57] , especialmente na fase aguda da doença. No entanto, não há estudos publicados que analisam os possíveis defeitos perfusionais e, ou inalatórios por segmentação pulmonar nos pacientes com granulomatose com poliangeíte tratados e em fase de remissão da doença.…”