“…Scholars segment the nodule in the CT images based on the distribution of the intensity [23]. Examples of the segmentation approaches in the literature are region growing [24], thresholding [25–27], a user‐interactive framework using 3D region growing on the fuzzy connectivity map [28] and based on grey‐level similarity and shape [29], voxel‐level and object‐level classification [30], region growing on the Euclidean distance map [31], active contour [15], anatomy packing with hierarchical segmentation [32], multi‐features clustering with adaptive local region energy [33], a modified deconvolutional neural network [34], deep learning methods [35–44], and graph cut with a deep learned prior [45].…”