Anatomy of the Male and Female Reproductive System

Jaffar, Mir; Bv, Srinivas

doi:10.5005/jp/books/12151_1

Cited by 1 publication

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“…The volume of secretion is small about 2-5% but rich in mucoproteins, which serves as a lubricant for the urethrae to facilitate ejaculations of the seminal fluid. The gland also produces the secretory immunoprotein-immunoglobulin G (IgG) [15].…”

Section: Accessory Sex Glandsmentioning

confidence: 99%

Testis and blood-testis barrier in Covid-19 infestation: role of angiotensin-converting enzyme 2 in male infertility

Olaniyan

Dare

Okotie

et al. 2020

Journal of Basic and Clinical Physiology and Pharmacology

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Severe acute respiratory syndrome coronavirus 2 (SARS- CoV-2) that causes COVID-19 infections penetrates body cells by binding to angiotensin-converting enzyme-2 (ACE2) receptors. Evidence shows that SARS-CoV-2 can also affect the urogenital tract. Hence, it should be given serious attention when treating COVID-19-infected male patients of reproductive age group. Other viruses like HIV, mumps, papilloma and Epstein–Barr can induce viral orchitis, germ cell apoptosis, inflammation and germ cell destruction with attending infertility and tumors. The blood-testis barrier (BTB) and blood-epididymis barrier (BEB) are essential physical barricades in the male reproductive tract located between the blood vessel and seminiferous tubules in the testes. Despite the significant role of these barriers in male reproductive function, studies have shown that a wide range of viruses can still penetrate the barriers and induce testicular dysfunctions. Therefore, this mini-review highlights the role of ACE2 receptors in promoting SARS-CoV-2-induced blood-testis/epididymal barrier infiltration and testicular dysfunction.

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Section: Accessory Sex Glandsmentioning

confidence: 99%