Anatomy of the Anterior Temporal Lobe and the Frontotemporal Region Demonstrated by Fiber Dissection

Peuskens, Diedrik; Loon, J. van; Calenbergh, Frank Van; Bergh, R. Van den; Goffin, Jan; Plets, Chris

doi:10.1227/01.neu.0000140843.62311.24

Cited by 106 publications

(142 citation statements)

References 39 publications

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“…Anything that would interfere with how these structures develop, how they respond to programmed cell death and pruning during critical developmental stages and how they interconnect, clearly implicates an integration problem across temporal lobe structures [22]. Thirdly, the fact that the TS-WM is implicated is very important because this region of the temporal lobe houses the majority of afferent/efferent connections to the temporal lobe [9]. It is a relatively small structure given the overall size of the temporal lobe, but subtle, strategic pathology at this level could have widespread disruption with regards to functional associations of the temporal lobe [10].…”

Section: Discussionmentioning

confidence: 99%

“…For example, there are five main temporal lobe gyri comprised of both white and gray matter , two critical limbic structures (hippocampus and amygdala) and their connections and a major white matter region -the temporal stem -comprised of much of the afferent/efferent connections of the temporal lobe with the rest of the brain [9,10]. At a minimum, taking just the aforementioned major regions equates to a total of 13 structures per hemisphere that can be isolated and studied, yielding a complex array of how these regions may differ or vary in comparison to one another and a statistical challenge as to how to control for family-wise error [11].…”

Section: Introductionmentioning

confidence: 99%

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Quantitative temporal lobe differences: Autism distinguished from controls using classification and regression tree analysis

Neeley

Bigler

Krasny

et al. 2007

Brain and Development

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SummaryThe temporal lobe is thought to be abnormal in autism, yet standard volumetric analyses are often unrevealing when age, sex, IQ and head size are controlled. Quantification of temporal lobe structures were obtained in male subjects with autism and controls, where subjects with head circumference (HC) defined macrocephaly were excluded, so that volume differences were not just related to the higher prevalence of macrocephaly in autism. Various statistical methods were applied to the analysis including a classification and regression tree (CART) method, a nonparametric technique that helps define patterns of relationships that may be meaningful in distinguishing temporal lobe differences between subjects with autism and age and IQ matched controls. Subjects with autism were also compared to a separate control group with reading disorder (RD), with the prediction that the temporal lobe morphometric analysis of the reading disorder controls would be more similar to that of the autism group. The CART method yielded a high specificity in classifying autism subjects from controls based on the relationship between the volume of the left fusiform gyrus (LFG) gray and white matter, the right temporal stem (RTS) and the right inferior temporal gyrus gray matter (RITG-GM). Reading disordered individuals were Publisher's Disclaimer: This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final citable form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain. Author Manuscript more similar to subjects with autism. Simple size differences did not distinguish the groups. These findings demonstrate different relationships within temporal lobe structures that distinguish subjects with autism from controls. Results are discussed in terms of pathological connectivity within the temporal lobe as it relates to autism. HHS Public Access

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Quantitative temporal lobe differences: Autism distinguished from controls using classification and regression tree analysis

Neeley

Bigler

Krasny

et al. 2007

Brain and Development

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“…Assim, as fibras que se projetam reciprocamente entre o tálamo e as regiões corticais que estão anteriores a esse "U" estão excluídas da cápsula interna, e são denominadas de pedúnculo talâmico extracapsular. Ture et al incluem nesse pedúnculo talâmico fibras provenientes da amígdala, do córtex temporal medial, e da substância inominada (Ture et al, 2000;Peuskens et al, 2004).…”

Section: Radiação Talâmicaunclassified

“…Esse feixe de fibras se origina da parte córtico-medial do complexo amigdaloide, e descreve um percurso em forma de "C" ao redor do tálamo, conectando a amígdala com a região septal. Seu trajeto é encontrado em uma depressão entre o tálamo e o núcleo caudado (Peuskens et al, 2004;Choi et al, 2011).…”

Section: Formação Hipocampal (Hipocampo Fórnice Comissura Hipocampal)unclassified

“…As fibras amígdalo-talâmicas constituem o chamado pedúnculo talâmico extracapsular. Para Peuskens et al (2004), a banda diagonal de Broca não estaria dentro do conceito da ansa peduncularis, mas a ansa lenticularis seria incluída também. A ansa lenticularis é um feixe fibras que conecta o globo pálido ao tálamo, e é encontrado posteriormente a essas outras fibras descritas.…”

Section: Formação Hipocampal (Hipocampo Fórnice Comissura Hipocampal)unclassified

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Anatomia microcirúrgica da região do sulco limitante inferior da ínsula

Ribas¹

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Combining fiber dissection, plastination, and tractography for neuroanatomical education: Revealing the cerebellar nuclei and their white matter connections

Arnts

Kleinnijenhuis

Kooloos

et al. 2013

Anatomical Sciences Ed

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In recent years, there has been a growing interest in white matter anatomy of the human brain. With advances in brain imaging techniques, the significance of white matter integrity for brain function has been demonstrated in various neurological and psychiatric disorders. As the demand for interpretation of clinical and imaging data on white matter increases, the needs for white matter anatomy education are changing. Because cross-sectional images and formalin-fixed brain specimens are often insufficient in visualizing the complexity of three-dimensional (3D) white matter anatomy, obtaining a comprehensible conception of fiber tract morphology can be difficult. Fiber dissection is a technique that allows isolation of whole fiber pathways, revealing 3D structural and functional relationships of white matter in the human brain. In this study, we describe the use of fiber dissection in combination with plastination to obtain durable and easy to use 3D white matter specimens that do not require special care or conditions. The specimens can be used as a tool in teaching white matter anatomy and structural connectivity. We included four human brains and show a series of white matter specimens of both cerebrum and cerebellum focusing on the cerebellar nuclei and associated white matter tracts, as these are especially difficult to visualize in two-dimensional specimens and demonstrate preservation of detailed human anatomy. Finally, we describe how the integration of white matter specimens with radiological information of new brain imaging techniques such as diffusion tensor imaging tractography can be used in teaching modern neuroanatomy with emphasis on structural connectivity.

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Anatomy of the Anterior Temporal Lobe and the Frontotemporal Region Demonstrated by Fiber Dissection

Cited by 106 publications

References 39 publications

Quantitative temporal lobe differences: Autism distinguished from controls using classification and regression tree analysis

Quantitative temporal lobe differences: Autism distinguished from controls using classification and regression tree analysis

Anatomia microcirúrgica da região do sulco limitante inferior da ínsula

Combining fiber dissection, plastination, and tractography for neuroanatomical education: Revealing the cerebellar nuclei and their white matter connections

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