Abstract:Various implant treatments, including total disc replacements, have been tried to treat lumbar intervertebral disc (IVD) degeneration, which is claimed to be the main contributor of lower back pain. The treatments, however, come with peripheral issues. This study proposes a novel approach that complies with the anatomical features of IVD, the so-called monolithic total disc replacement (MTDR). As the name suggests, the MTDR is a one-part device that consists of lattice and rigid structures to mimic the nucleus… Show more
“…An anatomy‐based configuration‐monolithic complete disc replacement constructed of TPU 87A and TPU 95A that was successfully created by Muhammad Hanif Nadhif and his team utilizing an FDM‐based 3D printing method while maintaining tolerable fabrication error rates. The two materials were predicted to degrade at rates that would last at least 4 years 117 . The application of personalized medicine benefits a formulation's therapeutic and safety since the drug may be easily modified to the patient's weight, sex, age, and genetic information.…”
Section: Applicationsmentioning
confidence: 99%
“…The two materials were predicted to degrade at rates that would last at least 4 years. 117 The application of personalized medicine benefits a formulation's therapeutic and safety since the drug may be easily modified to the patient's weight, sex, age, and genetic information. Verstraete et al with the use of FDM, TPU with high cross-over point and hardness values were found as potential excipients for the production of highly drug-loaded (unmilled metformic.HCL 60%, w/w) customized dosage forms.…”
Additive manufacturing is an emerging technology with the advantage of less wastage, fast prototyping with customized designing suitable for a wide range of applications. Three‐dimensional (3D) printing is one of the types of additive manufacturing and various polymers are explored for 3D printing applications. Thermoplastic polyurethane (TPU) is a versatile material that has gained increasing attention in 3D printing applications due to its unique combination of mechanical, thermal, and chemical properties. This review paper provides an overview of the current state‐of‐the‐art in TPU‐based 3D printing, including its characteristics, processing techniques, and mainly its applications. Extensive studies are done in TPU with fused deposition modeling (FDM), multi‐jet fusion (MJF), and selective laser sintering (SLS). The elasticity and flexibility, layer adhesion, tensile strength, and support structure are the parameters that decide the suitability of FDM, SLS, and MJF for TPU 3D printing. The infill density, modification of processing parameters, use of sacrificial materials, addition of perforations or channels, varying the particle size, using a mixture of powders, and so forth. leads to develop the porous structure in the final product. In addition, we have studied blends of TPU with other polymers like acrylonitrile butadiene styrene (ABS) and polylactic acid (PLA), as well as fiber‐reinforced TPU composites for 3D printing applications.
“…An anatomy‐based configuration‐monolithic complete disc replacement constructed of TPU 87A and TPU 95A that was successfully created by Muhammad Hanif Nadhif and his team utilizing an FDM‐based 3D printing method while maintaining tolerable fabrication error rates. The two materials were predicted to degrade at rates that would last at least 4 years 117 . The application of personalized medicine benefits a formulation's therapeutic and safety since the drug may be easily modified to the patient's weight, sex, age, and genetic information.…”
Section: Applicationsmentioning
confidence: 99%
“…The two materials were predicted to degrade at rates that would last at least 4 years. 117 The application of personalized medicine benefits a formulation's therapeutic and safety since the drug may be easily modified to the patient's weight, sex, age, and genetic information. Verstraete et al with the use of FDM, TPU with high cross-over point and hardness values were found as potential excipients for the production of highly drug-loaded (unmilled metformic.HCL 60%, w/w) customized dosage forms.…”
Additive manufacturing is an emerging technology with the advantage of less wastage, fast prototyping with customized designing suitable for a wide range of applications. Three‐dimensional (3D) printing is one of the types of additive manufacturing and various polymers are explored for 3D printing applications. Thermoplastic polyurethane (TPU) is a versatile material that has gained increasing attention in 3D printing applications due to its unique combination of mechanical, thermal, and chemical properties. This review paper provides an overview of the current state‐of‐the‐art in TPU‐based 3D printing, including its characteristics, processing techniques, and mainly its applications. Extensive studies are done in TPU with fused deposition modeling (FDM), multi‐jet fusion (MJF), and selective laser sintering (SLS). The elasticity and flexibility, layer adhesion, tensile strength, and support structure are the parameters that decide the suitability of FDM, SLS, and MJF for TPU 3D printing. The infill density, modification of processing parameters, use of sacrificial materials, addition of perforations or channels, varying the particle size, using a mixture of powders, and so forth. leads to develop the porous structure in the final product. In addition, we have studied blends of TPU with other polymers like acrylonitrile butadiene styrene (ABS) and polylactic acid (PLA), as well as fiber‐reinforced TPU composites for 3D printing applications.
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