Anatomical distribution and biochemical composition of urolithiasis in Kano, northern Nigeria

Emokpae, Mathias Abiodun; Gadzama, AA

doi:10.4314/ijbcs.v6i3.21

Cited by 6 publications

(12 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…2,4,5,10,11,15,25,28,30,38 In contrast to this, Nigerian authors identified the urinary bladder as the commonest location which was attributed by its endemicity and higher rate of poorly treated bladder out late obstruction in their study. [12][13][14]17 Alemu also demonstrated the common occurrence of urinary bladder stones in Mekelle, northern Ethiopia. 26 This could be partly due to the difference in the setup in which lower tract stones tend to be managed in a low resource setting and complex stones being referred to higher health facilities.…”

Section: Dovepressmentioning

confidence: 99%

“…12,16 Overall, the specific treatment relies on stone composition, site, size, number, patients' general condition and preference, and institutional capacity. [17][18][19] Despite the advancement of minimally invasive and noninvasive management of stone disease, which has become the gold standard treatment, open stone surgery remains the technique of choice in most developing countries. 2,3,16,20,21 This reflects the lack of trained professionals and endourologic instruments.…”

Section: Introductionmentioning

confidence: 99%

“… 12 , 16 Overall, the specific treatment relies on stone composition, site, size, number, patients’ general condition and preference, and institutional capacity. 17–19 …”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

<p>Urolithiasis: Presentation and Surgical Outcome at a Tertiary Care Hospital in Ethiopia</p>

Mohammed¹,

Yohannes²,

Tegegne³

et al. 2020

RRU

View full text Add to dashboard Cite

Background The prevalence of urolithiasis is on a rising trend in tropical and sub-Saharan African countries. The treatment options and data on the surgical outcome are limited in our country. This study was designed to assess the clinical presentation, surgical management and outcome of patients operated on for urolithiasis. Patients and Materials A retrospective study of all patients admitted and operated for urolithiasis at St. Paul’s hospital millennium medical college (SPHMMC) from July, 2016 to December, 2017 was conducted. Factors associated with surgical outcome were identified with binary logistic regression. Results Urolithiasis constituted 247 (30.0%) of 824 urologic admissions. Of these, 202 (Male:Female = 2:1) patients were investigated. The mean age was 37.1 ± 14.4 years (range, 10–85 years). The mean duration of illness was 16.7 ± 18.7 months and the commonest presenting symptom was isolated flank pain (97, 48.0%). A majority of the patients (186, 92.1%) had upper tract stones of which 96 (51.6%) were renal stones. More than two-thirds (164, 81.2%) of the patients had complications at presentation, and hydronephrosis (148, 73.3%) was the major one. Half of the patients (104, 51.5%) were treated with endoscopic procedures, 88 (43.6%) with open stone surgery and in 10 (4.9%) patients both were performed. Nephrectomy was done to 15 (7.4%) patients. Intraoperative and postoperative complications were noted in 16 (7.9%) and 26 (12.9%) patients, respectively. These complications were higher in patients with comorbid illness (AOR = 2.44; 95% CI 1.12–5.31; p = 0.024). Complete stone clearance was achieved in more than half of the clients (114, 61.0%). Multiple stones (AOR = 8.33; 95% CI 2.53–27.43; p < 0.0001) and endoscopic procedures (AOR = 4.17; 95% CI 1.57–10.71; p = 0.003) had significant association with incomplete stone clearance. Conclusion Patients’ presentation in this review was not different from studies elsewhere. Endoscopic procedures are emerging in our set up; however, it was significantly associated with incomplete stone clearance. Strategies to improve outcome (stone clearance) need to be implemented accordingly.

show abstract

Section: Dovepressmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

<p>Urolithiasis: Presentation and Surgical Outcome at a Tertiary Care Hospital in Ethiopia</p>

Mohammed¹,

Yohannes²,

Tegegne³

et al. 2020

RRU

View full text Add to dashboard Cite

show abstract

“…It is a common disorder estimated to occur in approximately 12% of the population with a recurrence rate of 70-80% in male and 47-60% in female [2]. In Nigeria, earlier reports on nephrolithiasis showed low prevalence until recent studies indicated a rising incidence of urolithiasis [3].…”

Section: Introductionmentioning

confidence: 99%

Effect of moonseed vine (Triclisia gilletii Staner) on ethane-1,2-diol-induced urolithiasis and its renotoxicity in Wistar albino rats

et al. 2020

View full text Add to dashboard Cite

Background: Moonseed vine (Triclisia gilletii Staner) in the family Menispermaceae is a robust creeper of up to 10 cm diameter, of the lowland dense rain forest. In Ondo State, located in the South Western part of Nigeria, the plant which is usually called Peshe is used for the management of renal-related ailments. The present study was undertaken to explore the efficacy of Triclisia gilletii, a folkloric therapy in the management of renal-related ailment. Results: Phenols, steroids, saponins, and flavonoids are present in the TGME with a total antioxidant capacity of (30.36 ± 1.90 (mg GAE/g extract), LD 50 greater than 5000 mg/kg b.w., and in vitro anti-nucleation activity (iC 50 = 7.09 mg/mL). Calcium oxalate stone formation as a result of oxalate from ethane-1,2-diol was evident by hypocalcemia, and further electrolyte imbalance and decreased glomerular filtration rate. The enhanced oxidative milieu in hyperoxaluria was evident by increased MDA and PC and decreased enzymatic and non-enzymatic antioxidants as well as renal membrane enzymes activities. The renal histopathological study further emphasized oxalateinduced damage and the ameliorative potential of TGME. Conclusion: The abnormal biochemical, redox electrolyte, membrane integrity, and histological alterations were attenuated by TGME which affirms its usage as nephroprotectant.

show abstract

“…Contrary to earlier studies that depicted urinary stone disease as being rare in Nigeria [4][5][6], a number of recent reports have shown an increasing incidence [7][8][9][10][11][12]. Although the reasons for this change in incidence rates remain speculative, rising socioeconomic development and climatic change in the Sub-Saharan nations have been advanced as possible causes [13].…”

Section: Introductionmentioning

confidence: 91%

A 5-Year Review of the Presentation and Management of Urolithiasis in a Nigerian Teaching Hospital

Omisanjo¹,

Bioku²,

Williams³

et al. 2019

View full text Add to dashboard Cite

show abstract

Anatomical distribution and biochemical composition of urolithiasis in Kano, northern Nigeria

Cited by 6 publications

References 0 publications

<p>Urolithiasis: Presentation and Surgical Outcome at a Tertiary Care Hospital in Ethiopia</p>

<p>Urolithiasis: Presentation and Surgical Outcome at a Tertiary Care Hospital in Ethiopia</p>

Effect of moonseed vine (Triclisia gilletii Staner) on ethane-1,2-diol-induced urolithiasis and its renotoxicity in Wistar albino rats

A 5-Year Review of the Presentation and Management of Urolithiasis in a Nigerian Teaching Hospital

Contact Info

Product

Resources

About