Anatomical and Physiological Aspects of the Capillary Bed in the Bulbar Conjunctiva of Man in Health and Disease

Re, Lee

doi:10.1177/000331975500600408

Cited by 16 publications

(2 citation statements)

References 9 publications

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“…The derivation or even estimation of shear rates in other parts of the microcirculation is hazardous, for acceptable definitions of flow rate in smaller arteries, arterioles, and venules have not been presented. Using photographic techniques, Lee has estimated that the blood flow in the "end arterioles" of the bulbar conjunctiva in man demonstrates a flow velocity of 0.11 mm per second (25). If one assumes that an end arteriole varies from 50 to 500 ,u in diameter, then in a vessel 100 ju wide, by the formula 4 V/r as above, blood in these arterioles would be subjected to a shear rate of about 10 sec-1.…”

Section: Discussionmentioning

confidence: 99%

Influence of Flow Properties of Blood Upon Viscosity-Hematocrit Relationships*

Wells¹,

Merrill²

1962

J. Clin. Invest.

205

100

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The influence of the red cell concentration (per cent hematocrit) upon blood viscosity is well known. Some physiology texts (1) portray this relationship by means of a diagram in which relative or apparent viscosity is plotted against the per cent hematocrit (Figure 1). It has been demonstrated that besides the effect of cell concentration the viscosity of blood varies both as a function of the shearing stresses developed within the fluid and the rate at which these forces are distributed between the adjacent fluid elements during flow (2-4). The relationship or ratio of shear stress to the gradient of velocity, or shear rate, defines the viscosity of the fluid in the absolute dimensions of dyne-seconds-cm', or poise. In his original definition of this property of fluids, Newton made the assumption that the ratio of shear stress to shear rate was constant for all fluids. Contemporary studies of the flow properties of various complex fluids have shown that many of these demonstrate a disproportionate change in shear stress as shear rate increases or decreases; in fact, rheological nomenclature is based upon the direction in which this ratio changes with change in shear rate (5,6).

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Section: Discussionmentioning

confidence: 99%

Influence of Flow Properties of Blood Upon Viscosity-Hematocrit Relationships*

Wells¹,

Merrill²

1962

J. Clin. Invest.

205

100

View full text Add to dashboard Cite

show abstract

“…The method permits observations of (a) a statistically valid sample of the patient's circulating arterial blood (16), (b) what may happen to the statistically valid sample as it passes into or through a peripheral vascular bed, and (c) the conditions of the bulbar conjunctival vessels, either normal or exhibiting the responses to injury delineated by Clark and Clark (17) and confirmed and extended by Brooks, Dragstedt, Warner, and Knisely (18). Variations of this method have been used by other investigators (3,(19)(20)(21)(22)(23)(24)(25)(26)(27)(28)(29).…”

Section: Methodsmentioning

confidence: 99%