Anatomical and pathological findings of renal aplasia and compensatory hypertrophy in a cat

Abstract

Summary:In this study incidentally detected renal aplasia in right kidney and compensatory hypertrophy in left kidney have been defined with the anatomical and pathological findings in a 2 years old male crossbred cat which had suffered from infirmity, vomiting, anorexia and depression. In macroscopic examination, it was observed that the left kidney was located on the left side of the median line, at the ventral part of the transverse processes of the 1 st -4 th lumbar vertebrae. The right kidney was at the right side of median line, ventral part of the transverse process of the 2 nd lumbar vertebra. Left kidney had a yellow color and a firm consistency and also the cut sections were smooth. Besides, right kidney had a grayish-yellow color and the distinction between renal cortex and medulla in cut sections couldn't be distinguished. As of anatomical location and morphology, no abnormality was observed in the other organs of the cat. In right kidney, tubular structures were recognized histopathologically in between intense collagen tissue. Numerous of vascular formations were found near to the renal capsule. In hypertrophic kidney, in many of the tubules, degenerative alterations were observed significantly. Microscopically the most of the glomeruli were enlarged with mesangial cell hyperplasia and filled completely the Bowman's space. In the light of the detailed anatomical and pathological findings, the aim of this study was to make a contribution to such unilateral aplasia and compensatory hypertrophy cases that were rarely detected both in human and veterinary medicine.