Anatomic Risk Factors for Diabetic Foot Ulceration

Tsapogas, Panagiotis

doi:10.1002/9781119255314.ch3

Cited by 1 publication

(2 citation statements)

References 10 publications

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“…Peripheral neuropathy and neuropathic foot ulcerations are well-known complications of long-standing diabetes mellitus [ 38 – 42 ]. These ulcerations usually affect prominent surfaces of the feet, such as the heel and metatarsal heads, or pressure point areas of high friction in combination with abnormally high pressures on the soles of the feet.…”

Section: Neuropathic Foot Ulcerations—diabetes Mellitusmentioning

confidence: 99%

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Neuropathic foot ulcers in the tallest patients with acromegalic gigantism: a common and significant problem. Historical overview

Herder

Raymond²

2023

Pituitary

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Purpose We present a historical overview on neuropathic ulcers in patients with acromegalic gigantism. Materials and methods The case histories of 6 famous patients with acromegalic gigantism and living in the twentieth century were analyzed. The combined final height and maximum weight of these giants were: 272 cm. & 215.9 kg., 218.4 cm. & 125 kg., 242 cm. & 165 kg., 220.5 cm. & 135 kg., 235 cm. & 136 kg. and 224.8 cm. & 174 kg. Conclusions Neuropathic foot ulcers leading to hospital admissions and surgical and medical interventions were reported in 6 patients with acromegalic gigantism. These ulcers significantly impaired the daily activities of these individuals. Neuropathies of the sural nerve in patients with acromegalic gigantism can lead to hypoesthesia and hypoalgesia of the lower legs and feet. Potential contributing factors for the development of neuropathic ulcers of the feet in patients with acromegalic gigantism and neuropathy might be leg and foot deformities, muscle weakness and poor quality footwear. Diabetes mellitus, or impaired glucose intolerance does not necessarily seem to play a role.

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Section: Neuropathic Foot Ulcerations—diabetes Mellitusmentioning

confidence: 99%

“…In diabetes mellitus, it is postulated that reactive oxygen species (ROS) within the tissues can lead to direct nerve injury. In combination with a lack of blood flow this can further lead to Charcot neuroarthropathy [ 38 – 42 ].…”

Section: Neuropathic Foot Ulcerations—diabetes Mellitusmentioning

confidence: 99%

Neuropathic foot ulcers in the tallest patients with acromegalic gigantism: a common and significant problem. Historical overview

Herder

Raymond²

2023

Pituitary

View full text Add to dashboard Cite

show abstract

Anatomic Risk Factors for Diabetic Foot Ulceration

Cited by 1 publication

References 10 publications

Neuropathic foot ulcers in the tallest patients with acromegalic gigantism: a common and significant problem. Historical overview

Neuropathic foot ulcers in the tallest patients with acromegalic gigantism: a common and significant problem. Historical overview

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