Anatomic-Functional Correlates of Adenosine-5’-Triphosphate Triggered Vagal Depressor Reflex

Pelleg, Amir; Hurt, Carl M.; Katchanov, Guennadi

doi:10.1007/978-1-4615-2011-5_34

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“…ATP and its metabolized form of adenosine is known to exert negative chronotropic and dromotropic effects on sinus node automaticity and AV nodal conduction. This effect is mediated by ATP's ability to suppress the sinus and AV nodes by transiently enhancing vagal tone in the heart (6)(7)(8). Therefore, it can be postulated that the remdesivir metabolite may exert the same deleterious effects on the conduction system J o u r n a l P r e -p r o o f…”

Section: Discussionmentioning

confidence: 99%

Remdesivir-induced symptomatic bradycardia in the treatment of COVID-19 disease

Jacinto¹,

Patel²,

Goh³

et al. 2021

HeartRhythm Case Reports

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Section: Discussionmentioning

confidence: 99%